• Official Full Name

    PTK7 protein tyrosine kinase 7

  • Overview

    Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.
  • Synonyms

    PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Cynomolgus / Rhesus macaque
  • Cynomolgus/Rhesus
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus monkey
  • E.coli
  • HEK293
  • HEK293T
  • Human cells
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • Yeast
  • C
  • Fc
  • DDK
  • DDK|His
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
  • N
  • SUMO
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PTK7-27862TH Recombinant Human PTK7 Wheat Germ N/A 110 amino acids
Human PTK7-669H Recombinant Human PTK7 Protein, DDK/His-tagged HEK293 DDK/His
Human PTK7-667H Recombinant Human PTK7 Protein, DDK/His-tagged HEK293 DDK/His
Human PTK7-183H Recombinant Human PTK7, GST-tagged Sf9 Insect Cell GST
Human PTK7-544H Recombinant Human PTK7 Protein, His-tagged E.coli His Leu853~Pro1070
Human PTK7-670H Recombinant Human PTK7 Protein, DDK/His-tagged HEK293 DDK/His
Human PTK7-668H Recombinant Human PTK7 Protein, DDK-tagged Sf9 Insect Cell DDK
Human PTK7-2697HCL Recombinant Human PTK7 293 Cell Lysate HEK293 N/A
Human PTK7-1202H Recombinant Human PTK7 Protein, His&SUMO-tagged E.coli N-His&SUMO Ala31-Phe333
Human PTK7-1659H Recombinant Human PTK7 Protein (31-704 aa), His-tagged Yeast His 31-704 aa
Human PTK7-1255H Recombinant Human PTK7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PTK7-0637H Recombinant Human PTK7 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ala31-Thr704
Human PTK7-1752H Recombinant Human PTK7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PTK7-01H Active Recombinant Human PTK7 Protein, Fc-tagged HEK293 Fc
Human PTK7-2109H Recombinant Human PTK7 protein, His-tagged HEK293 His Met1-Thr704
Mouse PTK7-13660M Recombinant Mouse PTK7 Protein, His and Myc tagged E.coli His and Myc
Mouse PTK7-7266M Recombinant Mouse PTK7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ptk7-5229M Recombinant Mouse Ptk7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PTK7-2181M Recombinant Mouse PTK7 protein, His-tagged HEK293 His Ala 23 - Thr 696
Mouse PTK7-2108M Recombinant Mouse PTK7 Protein, His-tagged Yeast His
Mouse PTK7-7266M-B Recombinant Mouse PTK7 Protein Pre-coupled Magnetic Beads HEK293
Rat Ptk7-2641R Recombinant Rat Ptk7 Protein, His-tagged E.coli N-His Gln502-Gln775
Rat PTK7-0634R Recombinant Rat PTK7 protein, Fc-tagged HEK293 Fc Ala23-Gln695
Rat PTK7-0633R Recombinant Rat PTK7 protein, His-tagged HEK293 His Ala23-Gln695
Rhesus monkey PTK7-3696R Recombinant Rhesus monkey PTK7 Protein, His-tagged HEK293 His Ala 39 - Thr 712
Rabbit PTK7-0636R Recombinant Rabbit PTK7 protein, His-tagged HEK293 His Ala31-Thr612
Cynomolgus PTK7-293C Recombinant Cynomolgus PTK7 Protein, 1-704, C-Fc-tagged Human cells C-Fc 1-704 aa
Cynomolgus / Rhesus macaque PTK7-0635C Recombinant Cynomolgus / Rhesus macaque PTK7 protein, His-tagged HEK293 His Ala39-Thr712
Cynomolgus/Rhesus PTK7-183C Recombinant Cynomolgus/Rhesus PTK7 protein, His-tagged HEK293 His Met1-Thr704
Chicken PTK7-2715C Recombinant Chicken PTK7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PTK7 involved in several pathways and played different roles in them. We selected most pathways PTK7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PTK7 has several biochemical functions, for example, ATP binding, protein binding, protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTK7 itself. We selected most functions PTK7 had, and list some proteins which have the same functions with PTK7. You can find most of the proteins on our site.

Function Related Protein
protein tyrosine kinase activityHCK;NTRK3A;WEE1;INSRB;PTK6B;TESK1;INSRA;NTRK2B;FGFR1B

PTK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTK7.

CTNNB1; CLNK; prfA; wnt3a

Research Area

Related articles

Gartner, S; Gunesch, A; et al. PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis Involvement. PLOS ONE 9:-(2014).
Zhao, WA; Cui, CH; et al. Bioinspired multivalent DNA network for capture and release of cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:19626-19631(2012).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
Does PTK7 have specific extracellular domains? 12/30/2021

Yes, PTK7 possesses extracellular domains, including a Wnt co-receptor domain, suggesting involvement in Wnt signaling pathways.

In which cellular processes does PTK7 participate? 11/07/2021

PTK7 is involved in diverse processes, including cell proliferation, migration, tissue morphogenesis, and planar cell polarity.

Are there potential therapeutic applications for PTK7? 10/29/2021

PTK7 is being explored as a potential therapeutic target, particularly in cancer treatment and tissue regeneration.

What role does PTK7 play in planar cell polarity? 04/10/2020

PTK7 plays a pivotal role in planar cell polarity, contributing to the alignment of cells and tissues during development.

What is the full name of PTK7? 06/04/2019

PTK7 stands for Protein Tyrosine Kinase 7.

What kind of protein is PTK7? 07/24/2018

PTK7 is a transmembrane receptor protein with tyrosine kinase activity.

Is PTK7 implicated in any diseases? 09/19/2016

Altered expression of PTK7 has been associated with various cancers, including colorectal cancer.

Customer Reviews (3)

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    We observed that results obtained with the product remained stable and reliable over long-term experiments.


      We appreciated that the product adhered to relevant regulatory standards, ensuring the ethical conduct of our experiments.


        The product's compliance with safety and ethical guidelines made it a responsible choice for our research endeavors.

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