PTK7
-
Official Full Name
PTK7 protein tyrosine kinase 7
-
Overview
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene. -
Synonyms
PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus
- Cynomolgus / Rhesus macaque
- Cynomolgus/Rhesus
- Human
- Mouse
- Rabbit
- Rat
- Rhesus monkey
- E.coli
- HEK293
- HEK293T
- Human cells
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- Yeast
- Fc
- Flag
- GST
- His
- Myc
- Avi
- SUMO
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
PTK7 involved in several pathways and played different roles in them. We selected most pathways PTK7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
PTK7 has several biochemical functions, for example, ATP binding, protein binding, protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTK7 itself. We selected most functions PTK7 had, and list some proteins which have the same functions with PTK7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DDX11;ATP8B5;ACTC1;LIG4;PTK2AB;ENTPD3;ABCA13;UBE2D4;MAP3K4 |
| protein binding | MYZAP;DDB2;HMGB1;ZCCHC11;TFAP2A;LIMA1;CCDC130;GNG5;COL6A5 |
| protein tyrosine kinase activity | KIT;EPHB4A;MAP2K6;DYRK2;TTK;PTK7;TESK1;FGFR1;MAP2K4 |
PTK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTK7.
CTNNB1; CLNK; prfA; wnt3a
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewWe observed that results obtained with the product remained stable and reliable over long-term experiments.
We appreciated that the product adhered to relevant regulatory standards, ensuring the ethical conduct of our experiments.
The product's compliance with safety and ethical guidelines made it a responsible choice for our research endeavors.
Q&As (7)
Ask a questionYes, PTK7 possesses extracellular domains, including a Wnt co-receptor domain, suggesting involvement in Wnt signaling pathways.
PTK7 is involved in diverse processes, including cell proliferation, migration, tissue morphogenesis, and planar cell polarity.
PTK7 is being explored as a potential therapeutic target, particularly in cancer treatment and tissue regeneration.
PTK7 plays a pivotal role in planar cell polarity, contributing to the alignment of cells and tissues during development.
PTK7 stands for Protein Tyrosine Kinase 7.
PTK7 is a transmembrane receptor protein with tyrosine kinase activity.
Altered expression of PTK7 has been associated with various cancers, including colorectal cancer.
Ask a Question for All PTK7 Products
Required fields are marked with *
My Review for All PTK7 Products
Required fields are marked with *
