• Official Full Name
  • son of sevenless homolog 1 (Drosophila)
  • Background
  • This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
  • Synonyms
  • SOS1; son of sevenless homolog 1 (Drosophila); GF1; HGF; NS4; GGF1; GINGF; son of sevenless homolog 1; SOS-1; guanine nucleotide exchange factor; gingival fibromatosis, hereditary, 1;
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SOS1
Source (Host):Species:Human
Product nameRecombinant Human SOS1 293 Cell Lysate