• Official Full Name
  • tenascin XB
  • Background
  • This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5 and 3 ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • TNXB; tenascin XB; TNXB1, TNXB2; tenascin-X; TNXBS; XB; XBS; Ehlers Danlos like syndrome; Hexabrachion like protein; HXBL; NXB2; Tenascin X precursor; Tenascin XB1; Tenascin XB2; TENX; TN X; TNX; TNXB1; TNXB2; hexabrachion-like protein; growth-inhibiting protein 45; TN-X
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human TNXB, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNXB, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNXB Protein, His-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tnxb protein, His & T7-tagged
Source (Host):Species:Human
Product nameRecombinant Human TNXB 293 Cell Lysate

TNXB Related Articles

Chen, XY; Li, R; et al. Identification of differentially expressed genes in hypothalamus of chicken during cold stress. MOLECULAR BIOLOGY REPORTS 41:2243-2248(2014).
Endo, T; Ariga, H; et al. Truncated form of tenascin-X, XB-S, interacts with mitotic motor kinesin Eg5. MOLECULAR AND CELLULAR BIOCHEMISTRY 320:53-66(2009).
Levy, P; Ripoche, H; et al. Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1. CLINICAL CANCER RESEARCH 13:398-407(2007).