Recombinant Human TNXB Protein, His-tagged

• Cat.No.: TNXB-607H
• Product Overview: Recombinant Human TNXB, transcript variant XB-S, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 73.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TNXB tenascin XB [ Homo sapiens ]
• Official Symbol: TNXB
• Synonyms: TNXB; tenascin XB; TNXB1, TNXB2; tenascin-X; TNXBS; XB; XBS; tenascin XB1; tenascin XB2; hexabrachion-like protein; growth-inhibiting protein 45; TNX; EDS3; HXBL; TENX; TN-X; TNXB1; TNXB2
• Gene ID: 7148
• mRNA Refseq: NM_019105
• Protein Refseq: NP_061978
• MIM: 600985
• UniProt ID: P22105