• Official Full Name

    ubiquitin specific peptidase 10

  • Overview

    Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and;degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme;specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and;cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in;the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene.
  • Synonyms

    USP10; ubiquitin specific peptidase 10; ubiquitin specific protease 10; ubiquitin carboxyl-terminal hydrolase 10; KIAA0190; UBPO; ubiquitin thioesterase 10; deubiquitinating enzyme 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • C
  • 6×His
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • His|SUMO
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human USP10-146H Recombinant Human USP10, His-SUMO-tagged E.coli His/SUMO
Human USP10-391H Recombinant Human USP10, Flag-tagged Insect Cell Flag
Human USP10-3615H Recombinant Human USP10, GST-tagged E.coli GST 444-798aa
Human USP10-474HCL Recombinant Human USP10 293 Cell Lysate HEK293 N/A
Human USP10-12H Recombinant Human USP10 Protein, His-tagged Insect Cell His
Human USP10-0545H Recombinant Human USP10 Protein (A2-L798), GST tagged E.coli GST A2-L798
Human USP10-01H Recombinant Human USP10 Protein, GST-tagged Insect Cell GST
Human USP10-11HFL Active Recombinant Full Length Human USP10 Protein, C-6×His tagged Insect Cell C-6×His Full Length
Human USP10-0546H Recombinant Human USP10 Protein (A2-L798), Tag Free E.coli No tag A2-L798
Human USP10-0547H Recombinant Human USP10 Protein (M1-E480), His/Strep tagged E.coli His/Strep M1-E480
Mouse USP10-17899M Recombinant Mouse USP10 Protein Mammalian Cell His
Mouse USP10-9947M-B Recombinant Mouse USP10 Protein Pre-coupled Magnetic Beads HEK293
Mouse USP10-9947M Recombinant Mouse USP10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat USP10-6469R Recombinant Rat USP10 Protein Mammalian Cell His
Rat USP10-6125R-B Recombinant Rat USP10 Protein Pre-coupled Magnetic Beads HEK293
Rat USP10-6125R Recombinant Rat USP10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken USP10-1282C Recombinant Chicken USP10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

USP10 involved in several pathways and played different roles in them. We selected most pathways USP10 participated on our site, such as DNA Damage Bypass, DNA Repair, Termination of translesion DNA synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Termination of translesion DNA synthesisUSP10;USP43;USP43A;KIAA0101;POLI
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA templateSPRTN;USP43;USP43A;POLI;USP10;KIAA0101

USP10 has several biochemical functions, for example, cysteine-type endopeptidase activity, ion channel binding, p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP10 itself. We selected most functions USP10 had, and list some proteins which have the same functions with USP10. You can find most of the proteins on our site.

Function Related Protein
cysteine-type endopeptidase activityCASP3A;PSD;ATG4B;CTSLL;USP13;USP37;USP9;FAM49BA;CTSC
ion channel bindingCALM1;KCNJ11;ID2;PIRT;LRRK2;KCNC1;KCND3;CDH5;KCNIP2
poly(A) RNA bindingNSBP1;SF3B14;ANXA2;PRDX1;UTP23;NMD3;DAP3;RPL7L1;DDX10
protein bindingTAS2R16;HSPBP1;UBE2V2;SULT2A1;TJP2;PBX1;SPIN1;CNOT2;CD200
ubiquitin-specific protease activityUSP13;USP20;USP17L5;USP28;COPS5;USP50;FAM105B;OTUD1;USP4

USP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP10.

G3BP2; YBX1; ZC3H12A; EIF4G3; ULK1; G3BP1; EIF4G1 variant protein; CELF1; GAR1; RAD51

Research Area

Related articles

Dauphinee, SM; Richer, E; et al. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections. GENES AND IMMUNITY 15:282-292(2014).
Feng, AP; He, YM; et al. Expression of USP15, T beta R-I and Smad7 in psoriasis. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 34:415-419(2014).
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