VPS29

  • Official Full Name

    vacuolar protein sorting 29 homolog (S. cerevisiae)

  • Background

    This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene.
  • Synonyms

    VPS29; vacuolar protein sorting 29 homolog (S. cerevisiae); vacuolar protein sorting 29 (yeast homolog) , vacuolar protein sorting 29 (yeast); vacuolar protein sorting-associated protein 29; DC7; DC15; PEP11; DKFZp564F0223; FLJ20492; hVPS29; PEP11 homolog; Retromer protein; Vacuolar protein sorting 29; Vacuolar protein sorting 29 (yeast homolog); Vacuolar protein sorting 29 (yeast); Vacuolar protein sorting 29 homolog; Vacuolar protein sorting associated protein 29; Vacuolar sorting protein VPS29/PEP11; Vesicle protein sorting 29; VPS 29; VPS29_HUMAN; x 007 protein;
    • Type:
    • Others
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C
    • Myc
    • DDK
    • His
    • His (Fc)
    • Avi
    • Strep
    • Myc|DDK
    • N/A
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    CBCRY38 Vacuolar Protein Sorting Protein 29 E.coli N/A
    Chicken VPS29-1762C Recombinant Chicken VPS29 Mammalian Cell His
    Human VPS29-016H Recombinant Human VPS29 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human VPS29-013H Recombinant Human VPS29 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human VPS29-0065H Recombinant Human VPS29 Protein (M1-P182), Tag Free E.coli No tag
    Human VPS29-0066H Recombinant Human VPS29 Protein (M1-P182), His/Strep tagged E.coli His/Strep
    Human VPS29-491H Recombinant Human VPS29 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Vps29-7397M Recombinant Mouse Vps29 Protein, His-tagged E.coli His
    Mouse VPS29-10064M Recombinant Mouse VPS29 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse VPS29-10064M-B Recombinant Mouse VPS29 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Vps29-6936M Recombinant Mouse Vps29 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse VPS29-18369M Recombinant Mouse VPS29 Protein Mammalian Cell His
    Rat VPS29-6198R-B Recombinant Rat VPS29 Protein Pre-coupled Magnetic Beads HEK293
    Rat VPS29-6542R Recombinant Rat VPS29 Protein Mammalian Cell His
    Rat VPS29-6198R Recombinant Rat VPS29 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Zebrafish VPS29-10392Z Recombinant Zebrafish VPS29 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    VPS29 involved in several pathways and played different roles in them. We selected most pathways VPS29 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EndocytosisACAP2;ARAP3;D6WSU116E;SNX6;IL2RA;DAB2;VPS45;SH3GLB1A;RAB11BA

    VPS29 has several biochemical functions, for example, metal ion binding, protein binding, contributes_to protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS29 itself. We selected most functions VPS29 had, and list some proteins which have the same functions with VPS29. You can find most of the proteins on our site.

    Function Related Protein
    metal ion bindingDPF2L;ZFP11;CYP2K6;PGM2L1;GTF2H3;NT5C2;AMY1B;ZNF599;GALNT13
    protein bindingALKBH3;EPO;DDX6;NOL12;NUP62;SYNJ2;MATR3;TLX2;GTF2H2C
    contributes_to protein transporter activityDNAJC15;TOMM5;VPS29;DNAJC19
    zinc ion bindingPHRF1;LHX4;OAS1;TRIM52;TRPS1;ADH8A;BAZ1A;TRIM35-34;ZFAND2A

    VPS29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS29 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS29.

    Vps26b; Vps26a; Ywhae; Pgls; Vps35

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