Recombinant Human SLC22A2 Protein (P2-N555), 8×His-Strep, Flag tagged

• Cat.No.: SLC22A2-0674H
• Product Overview: Recombinant Human 8His-Strep II-TEV-(GG)-SLC22A2(P2-N555)-Flag Protein was expressed in Insect cell.

Specification

• Description: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
• Source: Insect cell
• Species: Human
• Tag: 8His-Strep,Flag
• Form: Liquid
• Protein Length: P2-N555
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 70%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC22A2 solute carrier family 22 (organic cation transporter), member 2 [ Homo sapiens (human) ]
• Official Symbol: SLC22A2
• Synonyms: SLC22A2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2; OCT2; organic cation transporter 2; MGC32628
• Gene ID: 6582
• mRNA Refseq: NM_003058
• Protein Refseq: NP_003049
• MIM: 602608
• UniProt ID: O15244