slc2a1
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  • Official Full Name
  • solute carrier family 2 (facilitated glucose transporter), member 1
  • Background
  • This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
  • Synonyms
  • SLC2A1; solute carrier family 2 (facilitated glucose transporter), member 1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS; solute carrier family 2, facilitated glucose transporter member 1; GLUT-1; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; human T-cell leukemia virus (I and II) receptor;
Cat.#:SLC2A1-1753HTag:His/SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC2A1 protein, His & SUMO-tagged
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Cat.#:SLC2A1-2741HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC2A1, His-tagged
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Cat.#:SLC2A1-2742HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SLC2A1 protein, MYC/DDK-tagged
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Cat.#:SLC2A1-15359MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SLC2A1 Protein
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Cat.#:SLC2A1-5495RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SLC2A1 Protein
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Cat.#:SLC2A1-4263RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SLC2A1 Protein, His-tagged
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Cat.#:SLC2A1-6762CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SLC2A1
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Involved Pathway

SLC2A1 involved in several pathways and played different roles in them. We selected most pathways SLC2A1 participated on our site, such as HIF- signaling pathway, Insulin secretion, Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
HIF- signaling pathway
INSR; TEK; GM5506; MTOR; ALDOA; ANGPT1; PFKFB3; ANGPT2; PIK3CB; EGLN1
Insulin secretion
PRKACG; PRKCG; SLC2A1; CREB5; RAPGEF4; ATP1A2; ATP1A1; KCNMA1; GIP; INS2
Thyroid hormone signaling pathway
PLCG1; ATP1B3; SIN3A; MED17; PLCE1; MED12L; MAP2K2; DIO2; PFKP; ITGB3
Adipocytokine signaling pathway
ACSL5; RXRGB; ACSL3; AGRP; LEPB; SLC2A1A; ADIPOR1; ACSL3A; RXRB; PRKAG3
Glucagon signaling pathway
PDHB; PRKAG1; PRKACB; ITPR3; PPARGC1A; CAMK2A; CALM4; PPP3R1; FBP1; PPP3R2
Insulin resistance
MAPK8B; PPP1R3D; PCK1; PTEN; RPS6KA6; RPS6KB1; AKT1; TRIB3; PRKAG3B; PRKAB1A
Bile secretion
Adcy4; ABCC2; PRKACG; AQP1; GNAS; SLC51A; OSTA; OSTB; ATP1B3; SLC5A1
HTLV-I infection
WNT3A; HLA-DQB1; MAP3K1; WNT16; SLC25A6; CD3E; CD3D; Fzd4; POLE3; CD3G; PRKACA
Pathways in cancer
SPI1; MAX; FGFR3; LAMB2; GNG8; RAD51; FLT3LG; GNG12; RET; LAMC1
Renal cell carcinoma
HIF1A; PDGFB; RAC1; AKT2; EP300; PIK3R5; ETS1; PAK6; PIK3CA; EPAS1
Central carbon metabolism in cancer
SLC16A3; SCO2; RAF1; G6PD; HRAS; MAP2K1; PIK3R2; PFKM; SLC2A2; KRAS

Protein Function

SLC2A1 has several biochemical functions, for example, D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A1 itself. We selected most functions SLC2A1 had, and list some proteins which have the same functions with SLC2A1. You can find most of the proteins on our site.
Function
Related Protein
Function D-glucose transmembrane transporter activity
Related Protein SLC2A1; SLC2A13B; SLC2A2; SLC2A4
Function dehydroascorbic acid transporter activity
Related Protein SLC2A2; SLC2A1; SLC23A1
Function glucose transmembrane transporter activity
Related Protein SLC2A1; SLC2A11B; SLC2A9L1; SLC2A15A; PPBP; SLC2A4; SLC2A15B; SLC2A2; SLC2A1A; SLC2A3A
Function identical protein binding
Related Protein FBXW7; ATG16L1; TRIM55; USP2; SEPT7; IK; EGFR; DYNLT1B; ROBO2; NOL3
Function kinase binding
Related Protein CDC6; CTNNB1; JAKMIP1; ATF5; CEBPA; JAKMIP3; TENC1; LDHA; PARP16; PRDX3
Function protein binding
Related Protein PRKCQ; WFS1; ITGA5; C1QTNF1; ING4; SNX32; POLE3; KCNS2; CHCHD2; LRCH4
Function protein self-association
Related Protein EPB49; ZSWIM2; ZFP639; DYRK1A; TMEM190; PCSK9; BCL10; AGTR1B; S100A7A; TNFAIP3
Function xenobiotic transporter activity
Related Protein SLC2A1

Interacting Protein

SLC2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A1.
VCAM1; COPS6; E2F3; JAK2; STK17B; ATF2; TYK2; Bmpr1a; Cct8