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SLC40A1

  • Official Full Name

    solute carrier family 40 (iron-regulated transporter), member 1

  • Overview

    The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4). [provided by RefSeq, Jul 2008]
  • Synonyms

    SLC40A1; solute carrier family 40 (iron-regulated transporter), member 1; FPN1; HFE4; MTP1; IREG1; MST079; MSTP079; SLC11A3; solute carrier family 40 member 1; iron regulated gene 1; putative ferroportin 1 variant IIIA; putative ferroportin 1 variant IIIB; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Spleen
  • Insect Cell
  • Mammalian Cell
  • Protein Conjugation
  • Wheat Germ
  • 8His
  • MBP,Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
  • Tag
  • Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC40A1-7816H Recombinant Human SLC40A1 protein, His & GST-tagged E.coli His/GST Trp127~Val321 linked with LEHHHHHH
Human SLC40A1-1633HCL Recombinant Human SLC40A1 cell lysate N/A
Human SLC40A1-5335H Native Human Solute Carrier Family 40 (iron-regulated transporter), Member 1 Human Spleen N/A
Human SLC40A1-0628H Recombinant Human SLC40A1 Protein (T2-V571), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag T2-V571
Human SLC40A1-5842H Recombinant Human SLC40A1 Protein (Trp127-Val321), N-GST tagged E.coli N-GST Trp127-Val321
Human SLC40A1-26HFL Recombinant Full Length Human SLC40A1 Protein, N-GST-tagged Wheat Germ GST 1-571 a.a
Mouse SLC40A1-15445M Recombinant Mouse SLC40A1 Protein Mammalian Cell His
Mouse SLC40A1-8373M-B Recombinant Mouse SLC40A1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Slc40a1-2841M Recombinant Mouse Slc40a1 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Leu249-Leu265
Mouse SLC40A1-8373M Recombinant Mouse SLC40A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL17079HF Recombinant Full Length Human Solute Carrier Family 40 Member 1(Slc40A1) Protein, Tag-Free E.coli expression system Tag-Free Full Length (1-571)
Zebrafish SLC40A1-9167Z Recombinant Zebrafish SLC40A1 Mammalian Cell His
Chicken SLC40A1-2128C Recombinant Chicken SLC40A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC40A1 Related Articles

SLC40A1 involved in several pathways and played different roles in them. We selected most pathways SLC40A1 participated on our site, such as Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC40A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mineral absorptionATP1A1;ATP1A3;MT1G;SLC9A3;MT1E;MT2A;SLC8A1;TRPV6;ATP1B1

SLC40A1 has several biochemical functions, for example, ferrous iron transmembrane transporter activity, iron channel activity, iron ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC40A1 itself. We selected most functions SLC40A1 had, and list some proteins which have the same functions with SLC40A1. You can find most of the proteins on our site.

Function Related Protein
ferrous iron transmembrane transporter activitySLC39A14;SLC11A2;SLC40A1
iron channel activity
iron ion transmembrane transporter activitySLC40A1;TTYH1
peptide hormone bindingMC3R;AGTR1A;AGTR2;PTH1RB;MC4R;SLC40A1;AVPR1A;NPR2;HCRTR2
protein bindingAGL;TNIK;KAZN;COL1A1;CCDC167;RTP2;WFDC9;METAP2;CD63
receptor activityCSF2RA;CD226;CADM2A;CSF3R;GUCY1A3;OR3A2;BTN1A1;PVRL1B;TNFRSF11A

SLC40A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC40A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC40A1.

APP; CP; APP; Rps27a; ucpA; GOLM1

Lee, PL; Reid, TJ; et al. Sideroblastic anemia, iron overload, and ALAS2 R452S in African-American males: phenotype and genotype features of five unrelated patients. AMERICAN JOURNAL OF HEMATOLOGY 86:787-789(2011).
Canonne-Hergaux, F; Donovan, A; et al. Comparative studies of duodenal and macrophage ferroportin proteins. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 290:G156-G163(2006).
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