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Official Full Name solute carrier family 16 (monocarboxylate transporter), member 1
Background The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
Synonyms SLC16A1; solute carrier family 16 (monocarboxylate transporter), member 1; MCT; HHF7; MCT1; monocarboxylate transporter 1; MCT 1; solute carrier family 16 member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1);
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SLC16A1-54H Recombinant Human SLC16A1 Protein, GST-tagged Wheat Germ GST
    Human SLC16A1-1802HCL Recombinant Human SLC16A1 293 Cell Lysate HEK293 N/A
    Mouse SLC16A1-15227M Recombinant Mouse SLC16A1 Protein Mammalian Cell His
    Rat SLC16A1-5437R Recombinant Rat SLC16A1 Protein Mammalian Cell His
    Rhesus Macaque SLC16A1-4223R Recombinant Rhesus monkey SLC16A1 Protein, His-tagged Mammalian Cell His
    Chicken SLC16A1-1468C Recombinant Chicken SLC16A1 Mammalian Cell His
    Zebrafish SLC16A1-10438Z Recombinant Zebrafish SLC16A1 Mammalian Cell His

    slc16a1 involved in several pathways and played different roles in them. We selected most pathways slc16a1 participated on our site, such as Basigin interactions, Cell surface interactions at the vascular wall, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with slc16a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basigin interactions SLC7A8A; SLC7A11; SLC7A10; NADL1.1; SLC3A2A; PPIA; BSG; SLC3A2B; ITGB1B.1; SLC16A8
    Cell surface interactions at the vascular wall FCER1GL; SLC7A8A; MERTK; JAM2B; GRB7; NADL1.1; CXADR; CEACAM1; F11R.2; GAS6
    Metabolism BCKDK; SLC52A3; LBR; PNPLA8; KCNS3A; PLBD1; KHK; CSNK1G2; ACOT9.1; MED6
    Proton-coupled monocarboxylate transport SLC16A1; SLC16A7; SLC16A8
    Pyruvate metabolism ALDH2.1; BRP44; PDPR; PDK2B; PCXB; ALDH9A1A.1; SLC16A1; SLC16A8; LDHAL6B; FH1
    Pyruvate metabolism and Citric Acid (TCA) cycle PDK2B; SLC16A8; D2HGDH; ADHFE1; PDP1; PDK3B; PDK4; PDP2; PDK3; BRP44
    SLC-mediated transmembrane transport SLC1A3A; SLC43A2B; SLC6A1A; SLC3A2B; SLC15A3; SLC6A7; SLC5A2; SLC12A1; SLC35A3B; SLC26A1

    slc16a1 has several biochemical functions, for example, lactate transmembrane transporter activity, mevalonate transmembrane transporter activity, monocarboxylic acid transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by slc16a1 itself. We selected most functions slc16a1 had, and list some proteins which have the same functions with slc16a1. You can find most of the proteins on our site.

    Function Related Protein
    lactate transmembrane transporter activity SLC16A5; SLC16A12B; SLC16A8; SLC16A12; SLC16A3; SLC16A1; SLC5A12; SLC16A7
    mevalonate transmembrane transporter activity SLC16A1
    monocarboxylic acid transmembrane transporter activity SLC16A1; SLC16A6; PPP1R42; SLC16A4; SLC16A8; SLC16A9A; SLC16A9B; SLC16A6A; SLCO1A5; SLC16A3
    organic cyclic compound binding SLC16A1; MTNR1A
    protein homodimerization activity DMRT3; TOP2A; PVRL3B; CCBL2; CD200; SNX9; GIMAP7; RPE; USH1G; XBP1
    symporter activity SLC10A5; SLC6A18; PPP1R42; SLC38A4; SLC15A3; SLC17A7; SLC6A6; SLC24A4; SLC22A5; SLC24A2

    slc16a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with slc16a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of slc16a1.

    DEGS1; AP1S1; SERINC3; TSC22D1; TRAF6; ugpA; MME; Bmpr1a; ILK; Map3k12; P; FAM46A; MAP1LC3B

    Ahlin, G; Hilgendorf, C; et al. Endogenous Gene and Protein Expression of Drug-Transporting Proteins in Cell Lines Routinely Used in Drug Discovery Programs. DRUG METABOLISM AND DISPOSITION 37:2275-2283(2009).
    Palladino, AA; Bennett, MJ; et al. Hyperinsulinism in infancy and childhood: when an insulin level is not always enough. ANNALES DE BIOLOGIE CLINIQUE 67:245-254(2009).
    Palladino, AA; Bennett, MJ; et al. Hyperinsulinism in infancy and childhood: when an insulin level is not always enough. LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE 33:170-U3(2009).
    Palladino, AA; Bennett, MJ; et al. Hyperinsulinism in infancy and childhood: When an insulin level is not always enough. CLINICAL CHEMISTRY 54:256-263(2008).

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