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SLC25A4

  • Official Full Name

    solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

  • Overview

    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
  • Synonyms

    SLC25A4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; ANT1, PEO2, PEO3; ADP/ATP translocase 1; T1; ANT 1; ADP,ATP carrier protein 1; solute carrier family 25 member 4; heart/skeletal muscle ATP/ADP transloca;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Bovine
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC25A4-4962H Active Recombinant Human SLC25A4 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human SLC25A4-2727H Recombinant Human SLC25A4, His-tagged E.coli His 1-298aa
Human SLC25A4-1762HCL Recombinant Human SLC25A4 293 Cell Lysate HEK293 N/A
Mouse SLC25A4-15327M Recombinant Mouse SLC25A4 Protein Mammalian Cell His
Mouse Slc25a4-3221M Recombinant Mouse Slc25a4, His-tagged E.Coli or Yeast His 298
Mouse SLC25A4-8290M-B Recombinant Mouse SLC25A4 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC25A4-8290M Recombinant Mouse SLC25A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC25A4-5479R Recombinant Rat SLC25A4 Protein Mammalian Cell His
Rat SLC25A4-5138R Recombinant Rat SLC25A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC25A4-5138R-B Recombinant Rat SLC25A4 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL17241BF Recombinant Full Length Bovine Adp/Atp Translocase 1(Slc25A4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Bovine SLC25A4-3220B Recombinant Bovine SLC25A4, His-tagged E.Coli or Yeast His 298
Homo sapiens (Human) RFL30783HF Recombinant Full Length Human Adp/Atp Translocase 1(Slc25A4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Mus musculus (Mouse) RFL5287MF Recombinant Full Length Mouse Adp/Atp Translocase 1(Slc25A4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Oryctolagus cuniculus (Rabbit) RFL27785OF Recombinant Full Length Rabbit Adp/Atp Translocase 1(Slc25A4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Rattus norvegicus (Rat) RFL12022RF Recombinant Full Length Rat Adp/Atp Translocase 1(Slc25A4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Rhesus Macaque SLC25A4-4256R Recombinant Rhesus monkey SLC25A4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLC25A4-4072R Recombinant Rhesus Macaque SLC25A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLC25A4-4072R-B Recombinant Rhesus Macaque SLC25A4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLC25A4-12732Z Recombinant Zebrafish SLC25A4 Mammalian Cell His
Chicken SLC25A4-1583C Recombinant Chicken SLC25A4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC25A4 Related Articles

SLC25A4 involved in several pathways and played different roles in them. We selected most pathways SLC25A4 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPHKG2;SLC25A5;SLC8A1B;CHRNA7;CAMK2D;EGFRA;ADRB3B;CALM3B;PLCD1
cGMP-PKG signaling pathwayPPP1R12A;KCNMB4;NOS3;VDAC2;VDAC3;BAD;PRKG1;SLC25A4;TRPC6
Parkinsons diseaseVDAC1;NDUFB1;NDUFB8;UBE2J2;CASP9;NDUFA2;NDUFA12;NDUFS6;VDAC2
Huntingtons diseaseNDUFB2;CREB3L1;SLC25A6;CYCS;SOD2;NDUFS8;COX7A2;NDUFA6;ATP5A1
HTLV-I infectionMYBL2;SPI1;MAP2K4;CD3G;FZD2;KAT2A;TNFRSF13C;MAPK8;POLE2

SLC25A4 has several biochemical functions, for example, adenine transmembrane transporter activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A4 itself. We selected most functions SLC25A4 had, and list some proteins which have the same functions with SLC25A4. You can find most of the proteins on our site.

Function Related Protein
adenine transmembrane transporter activitySLC25A4;SLC25A5
protein bindingPTGDS;FAM96A;PBLD;KIAA1109;CTTN;AKAP7;ZFP932;SLIT2;FTCD

SLC25A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A4.

LRRK2; BCL2L13; TNFRSF1B; AR; q5nfy6_fratt; E2F3; Smad6; NS; PCNT; NS; M1; GRB2; a52_vaccw; ICT1

Di Noia, MA; Todisco, S; et al. The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters. JOURNAL OF BIOLOGICAL CHEMISTRY 289:33137-33148(2014).
Porcelli, V; Fiermonte, G; et al. The Human Gene SLC25A29, of Solute Carrier Family 25, Encodes a Mitochondrial Transporter of Basic Amino Acids. JOURNAL OF BIOLOGICAL CHEMISTRY 289:13374-13384(2014).
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