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SLC16A7

Official Full Name

solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Overview

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as;lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of;monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed;in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in;multiple transcript variants.
Synonyms

SLC16A7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2); solute carrier family 16 (monocarboxylic acid transporters), member 7; monocarboxylate transporter 2; MCT2; MCT 2; solute carrier family 16 member 7;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
Mouse
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC16A7-2700H	Recombinant Human SLC16A7, His-tagged	E.coli	His	C-46aa	$319 / 25ug
Mouse	SLC16A7-15237M	Recombinant Mouse SLC16A7 Protein	Mammalian Cell	His		Inquiry
Mouse	SLC16A7-8237M	Recombinant Mouse SLC16A7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SLC16A7-8237M-B	Recombinant Mouse SLC16A7 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)	RFL8219MF	Recombinant Full Length Meriones Unguiculatus Monocarboxylate Transporter 2(Slc16A7) Protein, His-Tagged	E.coli expression system	His	Full Length (1-71)	Inquiry
Zebrafish	SLC16A7-3529Z	Recombinant Zebrafish SLC16A7	Mammalian Cell	His		Inquiry
Chicken	SLC16A7-4416C	Recombinant Chicken SLC16A7	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC16A7 Related Articles

SLC16A7 involved in several pathways and played different roles in them. We selected most pathways SLC16A7 participated on our site, such as Proton-coupled monocarboxylate transport, SLC-mediated transmembrane transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC16A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Proton-coupled monocarboxylate transport	SLC16A8;SLC16A7;SLC16A1
SLC-mediated transmembrane transport	SLC26A3.1;SLC12A7;SLC28A2;SLC2A8;CTNS;SLC2A10;SLC4A1B;SLC1A7A;SLC35B3
Transmembrane transport of small molecules	SLC30A2;SLC26A7;ADD3A;LCN1;SLC6A11;CUTC;SLC5A9;SLC26A3.2;SLC29A1A
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	SLC22A7B.1;SLC2A10;SLC6A7;SLC5A11;SLC22A16;SLC6A20B;SLC6A9;SLC31A1;CP

SLC16A7 has several biochemical functions, for example, lactate transmembrane transporter activity, pyruvate secondary active transmembrane transporter activity, pyruvate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC16A7 itself. We selected most functions SLC16A7 had, and list some proteins which have the same functions with SLC16A7. You can find most of the proteins on our site.

Function	Related Protein
lactate transmembrane transporter activity	SLC16A12B;SLC16A1;SLC16A12;SLC5A12;SLC16A3;SLC16A7;SLC16A5;SLC16A8
pyruvate secondary active transmembrane transporter activity
pyruvate transmembrane transporter activity	BRP44;MPC1;SLC16A7
symporter activity	SLC38A3;SLC6A4A;SLC17A7;PPP1R42;SLC36A4;SLC16A13;SLC38A2;SLC16A12;SLC16A1

SLC16A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC16A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC16A7.

CPEB1

Merezhinskaya, N; Fishbein, WN; et al. Monocarboxylate transporters: Past, present, and future. HISTOLOGY AND HISTOPATHOLOGY 24:243-264(2009).