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SLC3A1

Official Full Name

solute carrier family 3, member 1
Overview

This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Synonyms

SLC3A1; solute carrier family 3, member 1; neutral and basic amino acid transport protein rBAT; D2; NAA-TR; b(0,+)-type amino acid transport protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC3A1-2767H	Recombinant Human SLC3A1, GST-tagged	E.coli	GST	336-685aa	$319 / 25ug
Human	SLC3A1-1715HCL	Recombinant Human SLC3A1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SLC3A1-6304H	Recombinant Human SLC3A1 Protein (Gly458-Leu607), N-His tagged	E.coli	N-His	Gly458-Leu607	Inquiry
Mouse	SLC3A1-15443M	Recombinant Mouse SLC3A1 Protein	Mammalian Cell	His		Inquiry
Mouse	Slc3a1-5932M	Recombinant Mouse Slc3a1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	SLC3A1-8372M-B	Recombinant Mouse SLC3A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SLC3A1-8372M	Recombinant Mouse SLC3A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SLC3A1-5537R	Recombinant Rat SLC3A1 Protein	Mammalian Cell	His		Inquiry
Rat	SLC3A1-5196R-B	Recombinant Rat SLC3A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SLC3A1-5196R	Recombinant Rat SLC3A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC3A1 involved in several pathways and played different roles in them. We selected most pathways SLC3A1 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC3A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Protein digestion and absorption	CPA2;PRSS2;COL10A1;SLC8A2;KCNN4;PRSS3;SLC3A1;CPB1;ATP1A1

SLC3A1 has several biochemical functions, for example, L-cystine transmembrane transporter activity, amino acid transmembrane transporter activity, basic amino acid transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC3A1 itself. We selected most functions SLC3A1 had, and list some proteins which have the same functions with SLC3A1. You can find most of the proteins on our site.

Function	Related Protein
L-cystine transmembrane transporter activity	CTNS;SLC1A4;SLC3A1
amino acid transmembrane transporter activity	SLC38A5;SLC6A17;SLC38A9;SLC36A4;SLC38A2;PEX3;SLC6A16B;SLC7A14;SLC7A2
basic amino acid transmembrane transporter activity	SLC7A7;SLC7A4;SLC3A1;PQLC2
catalytic activity	GTF2F2A;GOT1L1;DDAH2;ALDOCA;CWF19L1;DPYDB;PGAM1A;DBH;GMPR2
cation binding	SLC3A1;PPM1AA;PPM1DA;PPM1DB;PPM1NB;SLC3A2A;SLC3A2;PPM1LA;PPM1LB
protein binding	C10orf119;NPHP4;KLHL6;RNF40;TRMT12;ZNF167;SYMPK;S100A10;HDHD2
protein heterodimerization activity	Bcl2a1b;TP53;IKZF4;Itgam&Itgb2;GTF2A1;TAF6L;ITGA3;GTF2A2;SMC3

SLC3A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC3A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC3A1.