Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SLC7A11

  • Official Full Name

    solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

  • Overview

    This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
  • Synonyms

    SLC7A11; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; xCT; CCBR1; cystine/glutamate transporter; amino acid transport system xc-; solute carrier family 7 member 11; calcium channel blocker resistance protein CCBR1; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rhesus Macaque
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC7A11-49567H Active Recombinant Human SLC7A11 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human SLC7A11-30700TH Recombinant Human SLC7A11 protein, GST-tagged Wheat Germ GST
Human SLC7A11-1698HCL Recombinant Human SLC7A11 293 Cell Lysate HEK293 N/A
Human SLC7A11-01H Recombinant Human SLC7A11 Protein, His-tagged E. coli His
Human SLC7A11-301456H Recombinant Human SLC7A11 protein, GST-tagged E.coli GST Met211-Thr265
Human SLC7A11-2957H Active Recombinant Human SLC7A11 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-501aa
Human SLC7A11-301337H Recombinant Human SLC7A11 protein, GST-tagged E.coli GST Met1-Arg42
Human SLC7A11-11H Recombinant Human SLC7A11 Protein E.coli
Human SLC7A11-481HF Recombinant Full Length Human SLC7A11 Protein, GST-tagged In Vitro Cell Free System GST 501 amino acids
Mouse Slc7a11-2080M Recombinant Mouse Slc7a11 Protein, His-tagged E.coli N-His Ala287-Pro365
Homo sapiens (Human) RFL33376HF Recombinant Human Cystine/Glutamate Transporter(Slc7A11) Protein, His-Tagged E.coli expression system His Full Length (1-501aa)
Rhesus Macaque SLC7A11-4311R Recombinant Rhesus monkey SLC7A11 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLC7A11-4127R Recombinant Rhesus Macaque SLC7A11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLC7A11-4127R-B Recombinant Rhesus Macaque SLC7A11 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLC7A11 involved in several pathways and played different roles in them. We selected most pathways SLC7A11 participated on our site, such as Amino acid transport across the plasma membrane, Basigin interactions, Cell surface interactions at the vascular wall, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC7A11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino acid transport across the plasma membraneSLC3A2B;SLC6A20B;SLC3A2A;SLC36A2;SLC43A1A;SLC7A10;SLC6A19B;SLC7A3;SLC38A4
Basigin interactionsSLC3A2B;BSG;SLC7A6;SLC16A8;SLC3A2A;SLC16A1;SLC7A11;NADL1.1;SLC7A10
Cell surface interactions at the vascular wallESAMA;CEACAM1;SLC3A2A;SLC7A8A;SLC7A11;GRB14;FCER1GL;SLC16A8;GAS6
HemostasisS100A10B;IRF2A;CEACAM1;ZFPM1;MYB;HBD;HRG;HBG2;BSG
SLC-mediated transmembrane transportSLC39A8;SLC9A7;SLC29A2;SLC8A2A;SLC13A1;SLC3A2A;SLC38A3;SLC35A3A;RHCG
Transmembrane transport of small moleculesRHCG2A;SLC35D1A;SLCO4A1;ADD3;SLC4A3;TFA;SLC14A1;SLC22A7A;SLC38A4
Transport of inorganic cations/anions and amino acids/oligopeptidesSLC26A3;SLC38A3A;SLC38A5B;SLC6A20;SLC38A3;SLC12A4;SLC26A3.2;SLC12A3;SLC43A2B

SLC7A11 has several biochemical functions, for example, cystine:glutamate antiporter activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC7A11 itself. We selected most functions SLC7A11 had, and list some proteins which have the same functions with SLC7A11. You can find most of the proteins on our site.

Function Related Protein
cystine:glutamate antiporter activity
protein bindingMAGEA2B;ZNF155;NFKBIZ;CADM1;CCDC116;CDK5RAP3;AKR7A3;MC5R;TCF4

SLC7A11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC7A11 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC7A11.

CD44

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SLC7A11 Products

Required fields are marked with *

My Review for All SLC7A11 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends