SLC2A2
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Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 2
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Overview
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine,;and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for;glucose, it has been suggested as a glucose sensor. -
Synonyms
SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2; GLUT2; solute carrier family 2, facilitated glucose transporter member 2; GLUT-2; glucose transporter type 2, liver;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Sus scrofa (Pig)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Insect Cell
- Mammalian Cell
- Wheat Germ
- 8His
- MBP,Flag
- GST
- His
- His (Fc)
- Avi
- His|GST
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SLC2A2-28420TH | Recombinant Human SLC2A2 | Wheat Germ | N/A | 67 amino acids |
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| Human | SLC2A2-2744H | Recombinant Human SLC2A2, GST-tagged | E.coli | GST | 242-301aa | |
| Human | SLC2A2-0480H | Recombinant Human SLC2A2 Protein (T2-V524), 8×His-MBP, Flag tagged | Insect Cell | 8His-MBP,Flag | T2-V524 |
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| Human | SLC2A2-1781H | Recombinant Human SLC2A2 protein, His & GST-tagged | E.coli | His/GST | Cys239~Pro303 |
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| Mouse | SLC2A2-15363M | Recombinant Mouse SLC2A2 Protein | Mammalian Cell | His |
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| Mouse | SLC2A2-8312M-B | Recombinant Mouse SLC2A2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | SLC2A2-8312M | Recombinant Mouse SLC2A2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Sus scrofa (Pig) | RFL6763SF | Recombinant Full Length Pig Solute Carrier Family 2, Facilitated Glucose Transporter Member 2(Slc2A2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-120) |
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| Zebrafish | SLC2A2-3829Z | Recombinant Zebrafish SLC2A2 | Mammalian Cell | His |
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| Chicken | SLC2A2-7118C | Recombinant Chicken SLC2A2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- SLC2A2 Related Research Area
SLC2A2 involved in several pathways and played different roles in them. We selected most pathways SLC2A2 participated on our site, such as Insulin secretion, Prolactin signaling pathway, Type II diabetes mellitus, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin secretion | ATP1A1;CREB3L1;ATP1B4;KCNMB4;KCNMA1;TRPM4;PRKACA;FXYD2;CAMK2B |
| Prolactin signaling pathway | PIK3R1;HRAS;INS1;INS2;FOXO3;SOCS2;PRLR;MAP2K1;PIK3R2 |
| Type II diabetes mellitus | SOCS3;MTOR;INS1;PIK3R2;IRS2;PIK3R5;IKBKB;INS;INS2 |
| Insulin resistance | MAPK9;GYS1;PTPN1;CRTC2;PDPK1;SLC27A1A;PYGM;AKT3A;PPARGC1A |
| Maturity onset diabetes of the young | FOXA2;NKX6;MAFA;NEUROG3;HNF1B;BHLHA15;HES1;SLC2A2;INS2 |
| Carbohydrate digestion and absorption | AMY2A5;PLCB2;ATP1A2;PIK3R2;AKT2;ATP1A4;AMY2A;AMY1A;AMY1B |
| Central carbon metabolism in cancer | PDGFRA;PGAM1;PIK3CA;RET;G6PDX;NTRK3;SLC2A2;MAPK3;FGFR1 |
SLC2A2 has several biochemical functions, for example, D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A2 itself. We selected most functions SLC2A2 had, and list some proteins which have the same functions with SLC2A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| D-glucose transmembrane transporter activity | SLC2A13B;SLC2A4;SLC2A1;SLC2A2 |
| dehydroascorbic acid transporter activity | SLC2A2;SLC2A1;SLC23A1 |
| glucose transmembrane transporter activity | SLC2A9L1;SLC2A4;SLC2A1A;SLC2A3;SLC2A15B;SLC2A15A;SLC2A11B;SLC2A3A;SLC2A2 |
| hexose transmembrane transporter activity | |
| insulin receptor binding | DOK1;PHIP;GRB10;PTPN11;IGF2;IGF1;IGF1R;DOK2;SNX1 |
SLC2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A2.
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