SLC26A2
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Official Full Name
solute carrier family 26 (sulfate transporter), member 2 -
Overview
The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization. -
Synonyms
SLC26A2;solute carrier family 26 (sulfate transporter), member 2;DTD;sulfate transporter;DTDST;D5S1708;Diastrophic dysplasia protein;Diastrophic dysplasia sulfate transporter;EDM 4;EDM4;MST 153;MST153;MSTP 157;MSTP157;Solute carrier family 26 (sulfate transporter) member 2;Solute carrier family 26 member 2;Sulfate anion transporter 1;OTTHUMP00000160529
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC26A2-15340M | Recombinant Mouse SLC26A2 Protein | Mammalian Cells | Mouse | His |
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| SLC26A2-5483R | Recombinant Rat SLC26A2 Protein | Mammalian Cells | Rat | His |
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| SLC26A2-1754HCL | Recombinant Human SLC26A2 293 Cell Lysate | HEK293 | Human | Non |
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| SLC26A2-5142R | Recombinant Rat SLC26A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| SLC26A2-5142R-B | Recombinant Rat SLC26A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SLC26A2 involved in several pathways and played different roles in them. We selected most pathways SLC26A2 participated on our site, such as Biological oxidations,Cytosolic sulfonation of small molecules,Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC26A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biological oxidations | GGTLC1,ADH7,CYP2C19,CYP2C8,CYP2A13,CYP3A5,CYP21A2,NCOA2,GSTK1,CYP2K16 |
| Cytosolic sulfonation of small molecules | SULT1C2,SLC26A1,SULT2ST2,Sult2a6,SULT1B1,SULT1C4,SULT4A1,Sult2a2,SULT1ST6,SLC35B3 |
| Glycosaminoglycan metabolism | ST3GAL3A,GPC1B,VCANB,MAPK1IP1L,OMD,Gpc2,LYVE1,SLC35B2,GLB1L,B4GALT7 |
| SLC-mediated transmembrane transport | SLC2A15B,SLC16A7,SLC1A4,SLC43A2,SLC35B2,SLC35A3,SLC8A2A,SLC2A10,SLC15A2,SLC9A3.2 |
| Metabolism | ACMSD,CYP2K16,HAS3,SULT1B1,DHODH,NAGS,GNG13B,CIAO1,DPYDA.1,NUDT1 |
| Phase II conjugation | UGT1B4,SLC35B3,AS3MT,TPMT.2,UGT1B2,SULT2ST2,SLC26A1,SULT1C2,Sult2a2,SULT1C4 |
| Multifunctional anion exchangers | SLC26A3.2,SLC26A3,SLC26A1,SLC26A3.1,SLC26A6L,SLC26A7 |
| Metabolism of carbohydrates | SLC26A1,SLC25A12,SLC25A11,B3GAT2,SLC5A2,PYGMB,UST,GYG1B,HPSE,PFKLB |
Protein Function
SLC26A2 has several biochemical functions, for example, anion:anion antiporter activity,bicarbonate transmembrane transporter activity,chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC26A2 itself. We selected most functions SLC26A2 had, and list some proteins which have the same functions with SLC26A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| secondary active sulfate transmembrane transporter activity | SLC13A1,SLC26A11,SLC26A3.2,SLC26A3,SLC26A1,SLC26A7,SLC26A6L,SLC26A5,SLC26A3.1,SLC26A4 |
| bicarbonate transmembrane transporter activity | SLC26A9,SLC26A1,SLC26A3.2,SLC26A3,SLC26A4,SLC4A1,SLC4A1B,CFTR,SLC26A5,SLC26A6 |
| anion:anion antiporter activity | Slc4a2,SLC4A8,SLC26A6L,SLC22A9,SLC4A11,SLC26A9,SLC26A6,SLC26A5,SLC4A2B,SLC26A3.2 |
| sulfate transmembrane transporter activity | SLC26A11,SLC26A5,SLC26A3.1,SLC26A1,SLC26A3.2,SLC26A6,SLC26A7,SLC26A3,SLC26A4,SLC26A9 |
| oxalate transmembrane transporter activity | SLC26A4,SLC26A1,SLC26A3,SLC26A7,SLC26A6L,SLC26A3.1,SLC26A9,SLC26A11,SLC26A5,SLC26A3.2 |
| chloride channel activity | GABRA6,GABRR3,CFTR,CLIC1,SLC26A3.1,SLC26A3.2,CLIC2,CLIC5B,CLIC5,CLCC1 |
Interacting Protein
SLC26A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC26A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC26A2.
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