SLC9A3R2
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Official Full Name
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -
Overview
Na+/H+ exchanger regulatory factor 2 (NHERF2) is one of four proteins in the NHERF protein family. It is closely related to NHERF1 and, like NHERF1, contains two PDZ domains and a C-terminal ezrin/radixin/moesin (ERM) binding domain (EBD). Along with the -
Synonyms
SLC9A3R2;solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2;solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC9A3R2-2789H | Recombinant Human SLC9A3R2, GST-tagged | E.coli | Human | GST | 1-337aa | |
| SLC9A3R2-15531M | Recombinant Mouse SLC9A3R2 Protein | Mammalian Cells | Mouse | His |
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| SLC9A3R2-2053H | Recombinant Human SLC9A3R2 protein, His & T7-tagged | E.coli | Human | His&T7 | Leu56~Phe337 |
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| SLC9A3R2-1693HCL | Recombinant Human SLC9A3R2 293 Cell Lysate | HEK293 | Human | Non |
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| SLC9A3R2-8431M | Recombinant Mouse SLC9A3R2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SLC9A3R2-8431M-B | Recombinant Mouse SLC9A3R2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC9A3R2 involved in several pathways and played different roles in them. We selected most pathways SLC9A3R2 participated on our site, such as Aldosterone-regulated sodium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC9A3R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aldosterone-regulated sodium reabsorption | MAPK1,PIK3CD,IRS1,PIK3CA,PDPK1,INS2,PIK3R2,FXYD4,SGK1,INS1 |
Protein Function
SLC9A3R2 has several biochemical functions, for example, PDZ domain binding,beta-catenin binding,channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC9A3R2 itself. We selected most functions SLC9A3R2 had, and list some proteins which have the same functions with SLC9A3R2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex scaffold | ITSN1,MAGI3,HOMER1,CNOT1,MPP7,ISCU,CAPN3,PKP2,DLG1,WWC1 |
| receptor binding | MATK,GIPC1,PPP2R4,FGF11A,BAAT,CAPRIN2,WNT2BB,GNB2L1,CAT,CXCL12 |
| beta-catenin binding | PTPRJ,MED12L,GRIP1,APC,CXADR,CDH5,DVL3,SOX9,KDM6B,SALL1 |
| phosphatase binding | PPP1R36,SH3RF2,TRPC4AP,SH3GL1,CTSC,KLRAQ1,PPP1R21,PPARA,SH3YL1,SYTL2 |
| protein C-terminus binding | ATP2A2,PCGF1,JAK2,PEX1,MAPRE1,TOP2A,SIAH1,YAP1,GRIP1,SDCBP |
| PDZ domain binding | Apba1,DLC,LRP2,PLEKHA1,USHBP1,DOCK4,LIN7C,SDC2,ATP2B1A,LNX1 |
| channel regulator activity | CACNG8A,CNIH3,CACNG2B,CACNG7A,CACNG8,CACNG2,CACNG4,CACNG2A,SNF8,CACNG3 |
| protein binding | AHNAK2,Kitl,CLNS1A,ACTB,FOXH1,ATPAF2,MCC,HOXB5,P4HA3,EXOC3-AS1 |
| low-density lipoprotein particle receptor binding | LANCL1,SACS,LDLRAP1,MMP13,DNAJA1,APOE,APOEA,ARRB2,APOEB,MESDC2 |
Interacting Protein
SLC9A3R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC9A3R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC9A3R2.
CFTR;PTEN;SRY;Sry;SLC26A3
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References
- Shin, JB; Krey, JF; et al. Molecular architecture of the chick vestibular hair bundle. NATURE NEUROSCIENCE 16:365-374(2013).
- Padilla, J; Jenkins, NT; et al. Transcriptome-wide RNA sequencing analysis of rat skeletal muscle feed arteries. II. Impact of exercise training in obesity. JOURNAL OF APPLIED PHYSIOLOGY 116:1033-1047(2014).
