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SLC10A2

  • Official Full Name

    solute carrier family 10 (sodium/bile acid cotransporter family), member 2

  • Overview

    Ileal sodium/bile acid cotransporter also known as ileal sodium-dependent bile acid transporter (ISBT or IBAT) is a protein that in humans is encoded by the SLC10A2 (solute carrier family 10 member 2) gene.
  • Synonyms

    SLC10A2; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; ASBT, ISBT; ileal sodium/bile acid cotransporter; Na(+)-dependent ileal bile acid transporter; ileal sodium-dependent bile acid transporter; ileal apical sodium-dependent;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Human
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC10A2-529H Recombinant Human SLC10A2 Mammalian Cell His
Human SLC10A2-4064H-B Recombinant Human SLC10A2 Protein Pre-coupled Magnetic Beads HEK293
Human SLC10A2-01H Recombinant Human SLC10A2 Protein Wheat Germ
Human SLC10A2-3123H Recombinant Human SLC10A2 protein, His-tagged E.coli His 1-65 aa
Human SLC10A2-4064H Recombinant Human SLC10A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC10A2-5419R Recombinant Rat SLC10A2 Protein Mammalian Cell His
Rat SLC10A2-5078R Recombinant Rat SLC10A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC10A2-5078R-B Recombinant Rat SLC10A2 Protein Pre-coupled Magnetic Beads HEK293
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL34088CF Recombinant Full Length Cricetulus Griseus Ileal Sodium/Bile Acid Cotransporter(Slc10A2) Protein, His-Tagged E.coli expression system His Full Length (1-348)
Mus musculus (Mouse) RFL30289MF Recombinant Full Length Mouse Ileal Sodium/Bile Acid Cotransporter(Slc10A2) Protein, His-Tagged E.coli expression system His Full Length (1-348)
Oryctolagus cuniculus (Rabbit) RFL8538OF Recombinant Full Length Rabbit Ileal Sodium/Bile Acid Cotransporter(Slc10A2) Protein, His-Tagged E.coli expression system His Full Length (1-347)
Rattus norvegicus (Rat) RFL911RF Recombinant Full Length Rat Ileal Sodium/Bile Acid Cotransporter(Slc10A2) Protein, His-Tagged E.coli expression system His Full Length (1-348)
Zebrafish SLC10A2-10680Z Recombinant Zebrafish SLC10A2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC10A2 Related Articles
  • SLC10A2 Related Research Area

SLC10A2 involved in several pathways and played different roles in them. We selected most pathways SLC10A2 participated on our site, such as Bile secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC10A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Bile secretionOSTB;SLC2A1;ATP1B4;ADCY7;ABCC2;ADCY8;ABCB1;ATP1A4;BAAT

SLC10A2 has several biochemical functions, for example, bile acid:sodium symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC10A2 itself. We selected most functions SLC10A2 had, and list some proteins which have the same functions with SLC10A2. You can find most of the proteins on our site.

Function Related Protein
bile acid:sodium symporter activitySLC10A2;SLC10A3;SLC10A6;SLC10A4;SLC10A1

SLC10A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC10A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC10A2.

Soler, DM; Ghosh, A; et al. A single element in the 3 ' UTR of the apical sodium-dependent bile acid transporter controls both stabilization and destabilization of mRNA. BIOCHEMICAL JOURNAL 462:547-553(2014).
Geyer, J; Fernandes, CF; et al. Cloning and molecular characterization of the orphan carrier protein Slc10a4: Expression in cholinergic neurons of the rat central nervous system. NEUROSCIENCE 152:990-1005(2008).
Banerjee, A; Swaan, PW; et al. Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains. BIOCHEMISTRY 45:943-953(2006).
Duane, WC; Hartich, LA; et al. Diminished gene expression of ileal apical sodium bile acid transporter explains impaired absorption of bile acid in patients with hypertriglyceridemia. JOURNAL OF LIPID RESEARCH 41:1384-1389(2000).
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