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SLC36A2

Official Full Name

solute carrier family 36 (proton/amino acid symporter), member 2
Overview

This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria.
Synonyms

SLC36A2; solute carrier family 36 (proton/amino acid symporter), member 2; proton-coupled amino acid transporter 2; PAT2; TRAMD1; tramdorin; MGC119660; A530067G19Rik; FLJ16051; MGC119658; Proton coupled amino acid transporter 2; Proton/amino acid transporter 2; Solute carrier family 36 (proton/amino acid symporter) member 2; Solute carrier family 36 member 2; Tramdorin 1; tramdorin-1; OTTHUMP00000160624; OTTHUMP00000224111;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC36A2-2755H	Recombinant Human SLC36A2, His-tagged	E.coli	His	1-70aa	$319 / 25ug
Mouse	SLC36A2-15412M	Recombinant Mouse SLC36A2 Protein	Mammalian Cell	His		Inquiry
Mouse	SLC36A2-8346M	Recombinant Mouse SLC36A2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SLC36A2-8346M-B	Recombinant Mouse SLC36A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SLC36A2-5521R	Recombinant Rat SLC36A2 Protein	Mammalian Cell	His		Inquiry
Rat	SLC36A2-5180R-B	Recombinant Rat SLC36A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SLC36A2-5180R	Recombinant Rat SLC36A2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC36A2 Related Articles

SLC36A2 involved in several pathways and played different roles in them. We selected most pathways SLC36A2 participated on our site, such as Amino acid transport across the plasma membrane, Proton-coupled neutral amino acid transporters, SLC-mediated transmembrane transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC36A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Amino acid transport across the plasma membrane	SLC38A4;SLC7A11;SLC6A20B;SLC6A6;SLC38A3;SLC6A18;SLC6A20A;SLC1A4;SLC43A2
Proton-coupled neutral amino acid transporters
SLC-mediated transmembrane transport	SLC30A2;SLC22A18;SLC6A11;SLC2A13B;SLC39A8;SLC9A8;CP;SLC6A19B;SLC13A3
Transmembrane transport of small molecules	BEST3;LCN15;RHCGA;ASPH;AQP1A.1;GLRBA;SLC7A11;SLCO4A1;SLC39A6
Transport of inorganic cations/anions and amino acids/oligopeptides	SLC6A6;SLC38A3;SLC26A3;SLC17A7A;SLC20A1;SLC38A5B;SLC43A2;SLC7A3A;SLC12A7

SLC36A2 has several biochemical functions, for example, L-alanine transmembrane transporter activity, L-proline transmembrane transporter activity, glycine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC36A2 itself. We selected most functions SLC36A2 had, and list some proteins which have the same functions with SLC36A2. You can find most of the proteins on our site.

Function	Related Protein
L-alanine transmembrane transporter activity	SLC1A4;SLC36A3;SLC36A4;SLC36A2;SLC38A3;SLC36A1;SLC38A7
L-proline transmembrane transporter activity	SLC1A4;SLC6A7;SLC36A3;SLC6A20A;SLC36A1;SLC36A4;SLC36A2
glycine transmembrane transporter activity	SLC36A2;SLC38A5;SLC36A3;SLC38A5B;SLC36A1
hydrogen ion transmembrane transporter activity	ATP5G3B;ATP6V0A1B;ATP6V0D2;ATP6V0A1A;ATP5I;ATP6V0E;ATP5IA;ATP6V1F;ATP5H
hydrogen:amino acid symporter activity	SLC36A1;SLC36A3;SLC36A2

SLC36A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC36A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC36A2.

opuD

Schioth, HB; Roshanbin, S; et al. Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects. MOLECULAR ASPECTS OF MEDICINE 34:571-585(2013).

Zebisch, K; Brandsch, M; et al. Transport of L-proline by the proton-coupled amino acid transporter PAT2 in differentiated 3T3-L1 cells. AMINO ACIDS 44:373-381(2013).