SLC39A1
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Official Full Name
solute carrier family 39 (zinc transporter), member 1 -
Overview
Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene. -
Synonyms
SLC39A1;solute carrier family 39 (zinc transporter), member 1;zinc/iron regulated transporter like , ZIRTL;zinc transporter ZIP1;ZIP1;ZIP-1;hZIP1;zrt- and Irt-like protein 1;solute carrier family 39 member 1;solute carrier family 39 (zinc transpo
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC39A1-2760H | Recombinant Human SLC39A1, GST-tagged | E.coli | Human | GST | 1-100AA | |
| SLC39A1-2746H | Recombinant Human SLC39A1 protein, His-tagged | E.coli | Human | His | 90-179 aa | |
| SLC39A1-11862Z | Recombinant Zebrafish SLC39A1 | Mammalian Cells | Zebrafish | His |
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| SLC39A1-608HCL | Recombinant Human SLC39A1 lysate | HEK293 | Human | Non |
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| SLC39A1-1304H | Recombinant Human SLC39A1 Protein (126-179 aa), His-tagged | E.coli | Human | His | 126-179 aa |
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Involved Pathway
SLC39A1 involved in several pathways and played different roles in them. We selected most pathways SLC39A1 participated on our site, such as Metal ion SLC transporters,SLC-mediated transmembrane transport,Senescence and Autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC39A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Zinc influx into cells by the SLC39 gene family | SLC39A14,SLC39A7,SLC39A8,SLC39A10,SLC39A6,SLC39A3,SLC39A5,SLC39A2 |
| Zinc transporters | SLC39A7,SLC39A14,SLC39A10,SLC30A3,SLC39A6,SLC39A8,SLC30A2,SLC39A3,SLC39A5,SLC30A1B |
| Metal ion SLC transporters | SLC39A6,SLC39A5,SLC39A3,SLC30A5,SLC30A2,SLC39A7,SLC39A10,SLC39A8,SLC41A1,SLC39A2 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC13A4,SLC22A6,SLC5A4,RHCGA,SLC5A2,SLC2A7,SLC22A7B.1,SLC39A7,SLC2A15B,MATE4 |
| Senescence and Autophagy | ATG7,LC3,RB1CC1,GABARAP,IGFBP5,UVRAG,COL10A1,SLC39A2,IFI16,FKBP8 |
| Transmembrane transport of small molecules | SLC1A7B,TRPC5,TRPV3,SLC9A10,SLC30A8,ABCF1,SLC4A2A,ABCB8,SLC7A11,SLC22A15 |
| SLC-mediated transmembrane transport | SLC24A4A,SLC39A14,SLC3A2B,SLC13A4,SLC39A2,SLC16A8,SLC5A2,SLC2A6,SLC26A3.2,SLCO4A1 |
Protein Function
SLC39A1 has several biochemical functions, for example, inorganic cation transmembrane transporter activity,receptor binding,zinc ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC39A1 itself. We selected most functions SLC39A1 had, and list some proteins which have the same functions with SLC39A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | ANGPTL2,TIGIT,TRDN,ABL1,LRRC4B,IL29,ITGA1,CSK,FGG,APOF |
| zinc ion transmembrane transporter activity | SLC39A11,SLC39A14,SLC39A6,SLC39A12,SLC30A8,SLC30A1,SLC30A10,SLC30A6,SLC39A3,SLC30A5 |
| inorganic cation transmembrane transporter activity | SLC11A2,MMGT2 |
Interacting Protein
SLC39A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC39A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC39A1.
PLEKHM2;CERS2;q9wmx2-pro_0000037550
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References
- Michalczyk, AA; Ackland, ML; et al. hZip1 (hSLC39A1) regulates zinc homoeostasis in gut epithelial cells. GENES AND NUTRITION 8:475-486(2013).
