Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SLC16A2

  • Official Full Name

    solute carrier family 16, member 2 (thyroid hormone transporter)

  • Overview

    This gene encodes an integral membrane protein transporter of thyroid hormone; specifically, cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues including brain, heart, placenta, lung, kidney, skeletal muscle, and liver. This gene likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation.
  • Synonyms

    SLC16A2; solute carrier family 16, member 2 (thyroid hormone transporter); AHDS, Allan Herndon Dudley syndrome , DXS128, mental retardation, X linked 22 , MRX22, solute carrier family 16 (monocarboxylic acid transporters), member 2 , solute carrier fa;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • 8His
  • MBP,Flag
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC16A2-6784HF Recombinant Full Length Human SLC16A2 Protein In Vitro Cell Free System 461 amino acids
Human SLC16A2-87H Recombinant Human SLC16A2 Protein Wheat Germ N/A
Human SLC16A2-3340H Recombinant Human SLC16A2 Protein Wheat Germ N/A
Human SLC16A2-1346S Recombinant Human SLC16A2 Protein (A2-I539), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag A2-I539
Human SLC16A2-6790HF Recombinant Full Length Human SLC16A2 Protein In Vitro Cell Free System 1033 amino acids
Human SLC16A2-1345S Recombinant Human SLC16A2 Protein (M1-I539), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag M1-I539
Mouse SLC16A2-15233M Recombinant Mouse SLC16A2 Protein Mammalian Cell His
Mouse SLC16A2-8233M-B Recombinant Mouse SLC16A2 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC16A2-8233M Recombinant Mouse SLC16A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC16A2-5440R Recombinant Rat SLC16A2 Protein Mammalian Cell His
Rat SLC16A2-5099R Recombinant Rat SLC16A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC16A2-5099R-B Recombinant Rat SLC16A2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLC16A2-8222Z Recombinant Zebrafish SLC16A2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC16A2 Related Articles
  • SLC16A2 Related Research Area

SLC16A2 involved in several pathways and played different roles in them. We selected most pathways SLC16A2 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC16A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Thyroid hormone signaling pathwayMTOR;MED30;MDM2;SIN3A;SRC;THRA;PRKCA;PDPK1;PIK3R1

SLC16A2 has several biochemical functions, for example, symporter activity, thyroid hormone transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC16A2 itself. We selected most functions SLC16A2 had, and list some proteins which have the same functions with SLC16A2. You can find most of the proteins on our site.

Function Related Protein
symporter activitySLC17A1;SLC16A12B;SLC6A11;SLC6A4A;SLC16A12;SLC17A6;SLC16A13;SLC6A4B;SLC16A4
thyroid hormone transmembrane transporter activitySLC16A10;SLCO1A5;SLC16A2;SLCO1C1;SLCO4A1

SLC16A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC16A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC16A2.

Capri, Y; Friesema, ECH; et al. Relevance of Different Cellular Models in Determining the Effects of Mutations on SLC16A2/MCT8 Thyroid Hormone Transporter Function and Genotype-Phenotype Correlation. HUMAN MUTATION 34:1018-1025(2013).
Merezhinskaya, N; Fishbein, WN; et al. Monocarboxylate transporters: Past, present, and future. HISTOLOGY AND HISTOPATHOLOGY 24:243-264(2009).
Moeller, LC; Dumitrescu, AM; et al. Thyroid hormone responsive genes in cultured human fibroblasts. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 90:936-943(2005).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SLC16A2 Products

Required fields are marked with *

My Review for All SLC16A2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends