Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

SLC1A5

Official Full Name

solute carrier family 1 (neutral amino acid transporter), member 5
Overview

The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]
Synonyms

SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; neutral amino acid transporter B(0); ATB(0); RD114 virus receptor; baboon M7 virus receptor; neutral amino acid transporter B; solute carrier family 1 member 5; RD114/simian type D retrovirus receptor; sodium-dependent neutral amino acid transporter type 2;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Cynomolgus Monkey
Human
Zebrafish

Source

E.coli
HEK293
Insect Cell
Mammalian Cell

Tag

8His
MBP,Flag
GST
His
TrxA
His (Fc)
Avi
His|GST
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC1A5-0913H	Active Recombinant Human SLC1A5 Full Length Transmembrane protein(Nanodisc)	HEK293	N/A		Inquiry
Human	RDRC-2241H	Recombinant Human RDRC protein, GST-tagged	E.coli	GST	C-106aa	$319 / 25ug
Human	SLC1A5-1195H	Recombinant Human SLC1A5 protein, His & GST-tagged	E.coli	His/GST	Leu327~Met541 (Accession # Q15758)	Inquiry
Human	SLC1A5-1210H	Recombinant Human SLC1A5 Protein (A2-F921), 8×His-MBP, Flag tagged	Insect Cell	8His-MBP,Flag	A2-F921	Inquiry
Human	SLC1A5-1028H	Recombinant Human SLC1A5 protein, His & TrxA-tagged	E.coli	His & TrxA	Gln 154 - Gln 224	Inquiry
Cynomolgus Monkey	SLC1A5-922C	Recombinant Cynomolgus SLC1A5 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	SLC1A5-665C-B	Recombinant Cynomolgus Monkey SLC1A5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	SLC1A5-665C	Recombinant Cynomolgus Monkey SLC1A5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	SLC1A5-7769Z	Recombinant Zebrafish SLC1A5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC1A5 Related Articles

SLC1A5 involved in several pathways and played different roles in them. We selected most pathways SLC1A5 participated on our site, such as Protein digestion and absorption, Central carbon metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Protein digestion and absorption	SLC8A1;CELA2A;COL7A1;ATP1B2;COL6A4;SLC3A2;KCNN4;PRSS3;KCNE3
Central carbon metabolism in cancer	IDH1;PIK3R3;PKM;PDGFRA;HK1;PIK3CD;PGAM2;FGFR3;G6PDX

SLC1A5 has several biochemical functions, for example, L-glutamine transmembrane transporter activity, neutral amino acid transmembrane transporter activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A5 itself. We selected most functions SLC1A5 had, and list some proteins which have the same functions with SLC1A5. You can find most of the proteins on our site.

Function	Related Protein
L-glutamine transmembrane transporter activity	SLC38A3;SLC38A1;SLC1A4;SLC38A7;SLC1A5
neutral amino acid transmembrane transporter activity	SLC1A5;SLC43A2;SLC43A2B;SLC43A1A;SLC38A5;SLC6A19B;SLC3A2;SLC7A8;SLC7A10
protein binding	ITGAM;SLC22A7;ITGB4;NAT8;CEP85;OTX2;TIMM21;MTAP1B;PMEPA1
receptor activity	ANTXR2B;LRP1;ITGB1B.1;ADIPOR2;GRIA3B;VMN1R52;P2RY2;FPR3;NR2C2
sodium:dicarboxylate symporter activity	SLC1A2;SLC1A3A;SLC1A3;SLC1A7A;SLC1A2A;SLC1A5;SLC1A7;SLC13A5;SLC1A1
virus receptor activity	TNFRSF14;TYRO3;NPC1;MOG;GPR172B;CD209;MRC1;SCARB2;ITGB6

SLC1A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A5.

RNF5; bnps-skatole; ganglioside_gm1; 4504987; MPDU1; USP19; TNFRSF1A; TNFRSF1B; HLA-B; MAP3K1; USP50; NEK6; GSTK1; TBC1D17; 15-deoxy-delta(12,14

Indo, Y; Takeshita, S; et al. Metabolic Regulation of Osteoclast Differentiation and Function. JOURNAL OF BONE AND MINERAL RESEARCH 28:2392-2399(2013).

Metzler, R; Meleshkevitch, EA; et al. An SLC6 transporter of the novel B-0,B-- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. JOURNAL OF EXPERIMENTAL BIOLOGY 216:2843-2857(2013).