AVP

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AVP

Official Full Name arginine vasopressin
Background This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
Synonyms AVP; arginine vasopressin; VP; ADH; ARVP; AVRP; AVP-NPII; vasopressin-neurophysin 2-copeptin; neurohypophyseal; prepro-AVP-NP II; antidiuretic hormone; vasopressin-neurophysin II-copeptin; prepro-arginine-vasopressin-neurophysin II;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AVP-1043H Recombinant Human AVP protein, GST-tagged GST
    Human AVP-3033H Recombinant Human AVP Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human AVP-8222H Recombinant Human AVP protein, His & T7-tagged E.coli His/T7
    Mouse AVP-2213M Recombinant Mouse AVP Protein Mammalian Cell His
    Mouse Avp-8223M Recombinant Mouse Avp protein, His-tagged E.coli His
    Rat Avp-8224R Recombinant Rat Avp protein, His-tagged E.coli His
    Rat AVP-905R Recombinant Rat AVP Protein Mammalian Cell His
    Chicken AVP-6740C Recombinant Chicken AVP Mammalian Cell His
    Zebrafish AVP-9589Z Recombinant Zebrafish AVP Mammalian Cell His

    AVP involved in several pathways and played different roles in them. We selected most pathways AVP participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with AVP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phospholipase D signaling pathway PLA2G4A; F2R; CYTH4; MAPK3; PLCB3; CXCR2; PPAP2A; MAPK1; PIP5K1A; PLCB4
    Vasopressin-regulated water reabsorption AQP2; AQP4; RAB5C; RAB11B; CREB3L2; VAMP2; DYNLL1; PRKACB; DYNC1LI2; DCTN6

    AVP has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by AVP itself. We selected most functions AVP had, and list some proteins which have the same functions with AVP. You can find most of the proteins on our site.

    Function Related Protein
    V1A vasopressin receptor binding AVPR1A; AVP
    V1B vasopressin receptor binding AVP
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process SERPINB9; C1QL4L; XIAP; SERPINB1A; PRDX5; IGF1RB; NOL3; PRDX3; ARRB1; BIRC5
    hormone activity URP2; GPHA2; ADM; INHBB; CCK; Gh; CCL25; INSL5B; PRL8A9; SST
    neurohypophyseal hormone activity AVP; OXT
    neuropeptide hormone activity ADCYAP1; CCK; CORT; PPY; AGRP; NTS; NPFFL; CRH; PYY; VIP
    protein kinase activity CSNK1E; EPHA4A; BSK146; MMD; STK24B; PRKCZ; GSK3AB; ARAF; CAMKK1B; MAP3K12
    signal transducer activity LSP1; CD40; EMR4; TMEM9B; SH2B2; PLCD4; GNAZ; STAT4; OLFR958; IL15RA

    AVP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AVP here. Most of them are supplied by our site. Hope this information will be useful for your research of AVP.

    Altmann, DM; et al. Host immunity to Bacillus anthracis lethal factor and other immunogens: implications for vaccine design. EXPERT REVIEW OF VACCINES 14:429-434(2015).
    Moriya, T; Shibasaki, R; et al. Full-length transient receptor potential vanilloid 1 channels mediate calcium signals and possibly contribute to osmoreception in vasopressin neurones in the rat supraoptic nucleus. CELL CALCIUM 57:25-37(2015).

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