avp
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  • Official Full Name
  • arginine vasopressin
  • Background
  • This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
  • Synonyms
  • AVP; arginine vasopressin; VP; ADH; ARVP; AVRP; AVP-NPII; vasopressin-neurophysin 2-copeptin; neurohypophyseal; prepro-AVP-NP II; antidiuretic hormone; vasopressin-neurophysin II-copeptin; prepro-arginine-vasopressin-neurophysin II;
Cat.#:AVP-3033HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human AVP Protein, MYC/DDK-tagged
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Cat.#:AVP-1043HTag:GST
Source (Host):Species:Human
Product nameRecombinant Human AVP protein, GST-tagged
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Cat.#:AVP-8222HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AVP protein, His & T7-tagged
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Cat.#:AVP-2213MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AVP Protein
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Cat.#:Avp-8223MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Avp protein, His-tagged
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Cat.#:Avp-8224RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Avp protein, His-tagged
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Cat.#:AVP-905RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AVP Protein
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Cat.#:AVP-6740CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AVP
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Cat.#:AVP-9589ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AVP
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Involved Pathway

AVP involved in several pathways and played different roles in them. We selected most pathways AVP participated on our site, such as Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with AVP were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phospholipase D signaling pathway
PIK3R3; RRAS2; Pdgfa&Pdgfb; RHOA; PLCG1; LPAR3; MTOR; PLCB1; CXCR2; GNAS
Vasopressin-regulated water reabsorption
STX4; STX4A; DYNLL1; PRKACA; AVP; AQP3; PRKACG; VAMP2; CREB3L3; DCTN5

Protein Function

AVP has several biochemical functions, for example, V1A vasopressin receptor binding, V1B vasopressin receptor binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by AVP itself. We selected most functions AVP had, and list some proteins which have the same functions with AVP. You can find most of the proteins on our site.
Function
Related Protein
Function V1A vasopressin receptor binding
Related Protein AVP; AVPR1A
Function V1B vasopressin receptor binding
Related Protein AVP
Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Related Protein TNFSF14; NAIP1; ARRB1; MT3; PRDX5; BIRC2; IGF1RB; IGF1RA; NOL3; SERPINB9
Function hormone activity
Related Protein POMC; APLN; INHA; PTHLHA; TSHB; PPY; RETNLB; GNRH3; PRL6A1; INSL5B
Function neurohypophyseal hormone activity
Related Protein OXT; AVP
Function neuropeptide hormone activity
Related Protein PYY; CALCB; GAL; UCN; TRH; ADCYAP1; PPY; NPFF; GRP; AVP
Function protein kinase activity
Related Protein PHKG1B; CDC42BPB; RPS6KA3B; MAP3K11; PDK4; CDK12; PTK2; CSNK1E; SCYL2; SRPK1B
Function signal transducer activity
Related Protein PTGER4B; TAAR14D; ILK; MUL1; JUP; VMN1R40; RRH; SECTM1; OLFR49; OXTRL

AVP Related Articles

Altmann, DM; et al. Host immunity to Bacillus anthracis lethal factor and other immunogens: implications for vaccine design. EXPERT REVIEW OF VACCINES 14:429-434(2015).
Moriya, T; Shibasaki, R; et al. Full-length transient receptor potential vanilloid 1 channels mediate calcium signals and possibly contribute to osmoreception in vasopressin neurones in the rat supraoptic nucleus. CELL CALCIUM 57:25-37(2015).