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BCMO1

  • Official Full Name

    beta-carotene 15,15-monooxygenase 1

  • Overview

    Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
  • Synonyms

    BCMO1; beta-carotene 15,15-monooxygenase 1; BCDO, BCDO1, beta carotene 15, 15 dioxygenase 1; beta,beta-carotene 15,15-monooxygenase; BCMO; FLJ10730; beta-carotene dioxygenase 1; beta-carotene 15, 15-dioxygenase 1; BCO; BCDO; BCO1; BCDO1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BCMO1-170H Recombinant Human BCMO1 Protein, GST-tagged Wheat Germ GST
Human BCMO1-10192H Recombinant Human BCMO1, His-tagged E.coli His 199-547a.a.
Human BCMO1-26H Recombinant Human BCMO1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BCMO1-171H Recombinant Human BCMO1 Protein, GST-tagged Wheat Germ GST
Human BCMO1-8474HCL Recombinant Human BCMO1 293 Cell Lysate HEK293 N/A
Human BCMO1-1554HF Recombinant Full Length Human BCMO1 Protein, GST-tagged In Vitro Cell Free System GST 547 amino acids
Human BCMO1-2006HFL Recombinant Full Length Human BCMO1 protein, Flag-tagged Mamanlian cells Flag
Human BCMO1-132H Recombinant Human BCMO1 Protein, His-tagged E. coli His
Rat BCMO1-962R Recombinant Rat BCMO1 Protein Mammalian Cell His
Rat BCMO1-620R Recombinant Rat BCMO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat BCMO1-620R-B Recombinant Rat BCMO1 Protein Pre-coupled Magnetic Beads HEK293
Chicken BCMO1-6203C Recombinant Chicken BCMO1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BCMO1 Related Articles

BCMO1 involved in several pathways and played different roles in them. We selected most pathways BCMO1 participated on our site, such as Retinol metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Retinol metabolismCYP3A25;CYP2C55;UGT1A6;CYP2C39;UGT2B15;CYP2C50;UGT2A1;UGT1A2;UGT1A7
Metabolic pathwaysAKR1B1L;FUT9;CYP2B6;NMRK1;POLR2K;ALAS2;NDUFA8;FTCD;CKMT2B

BCMO1 has several biochemical functions, for example, beta-carotene 15,15-monooxygenase activity, metal ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCMO1 itself. We selected most functions BCMO1 had, and list some proteins which have the same functions with BCMO1. You can find most of the proteins on our site.

Function Related Protein
beta-carotene 15,15-monooxygenase activityBCMO1;BCO1
metal ion bindingKLF11B;AMDHD1;ZNF571;PPM1K;SOBPB;FREM2;GALNT10;TOPAZ1;GALNTL2
monooxygenase activityCYP1A4;CYP2AD6;CYP2K6;CYP21A1;CYP3A7;CYP2E1;CYP17A2;CYP2AD3;CYP2K18

BCMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCMO1.

MYC

Zubair, N; Kooperberg, C; et al. Genetic Variation Predicts Serum Lycopene Concentrations in a Multiethnic Population of Postmenopausal Women. JOURNAL OF NUTRITION 145:187-192(2015).
Yamaguchi, N; Sunto, A; et al. Competitive regulation of human intestinal beta-carotene 15,15 '-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear factor (HNF)-1 alpha and HNF-4 alpha. LIFE SCIENCES 119:34-39(2014).
  • Q&As
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