Recombinant Human BCMO1 protein, MYC/DDK-tagged

• Cat.No.: BCMO1-26H
• Product Overview: Recombinant Human BCMO1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 62.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: BCMO1 beta-carotene 15,15-monooxygenase 1 [ Homo sapiens ]
• Official Symbol: BCMO1
• Synonyms: BCMO1; beta-carotene 15,15-monooxygenase 1; BCDO, BCDO1, beta carotene 15, 15 dioxygenase 1; beta,beta-carotene 15,15-monooxygenase; BCMO; FLJ10730; beta-carotene dioxygenase 1; beta-carotene 15, 15-dioxygenase 1; BCO; BCDO; BCO1; BCDO1
• Gene ID: 53630
• mRNA Refseq: NM_017429
• Protein Refseq: NP_059125
• MIM: 605748
• UniProt ID: Q9HAY6
• Chromosome Location: 16q23.2
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Retinol metabolism, organism-specific biosystem; Retinol metabolism, conserved biosystem; Vitamin A and carotenoid metabolism, organism-specific biosystem
• Function: beta-carotene 15,15-monooxygenase activity; beta-carotene 15,15-monooxygenase activity; metal ion binding; monooxygenase activity