camk2b
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  • Official Full Name
  • calcium/calmodulin-dependent protein kinase II, beta
  • Background
  • CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
  • Synonyms
  • CAMK2B; calcium/calmodulin-dependent protein kinase II, beta; Camk2d; calcium/calmodulin-dependent protein kinase type II subunit beta; CaMK II; caMK-II subunit beta; caM kinase II subunit beta; calcium/calmodulin-dependent protein kinase II, delta;
Cat.#:CAMK2B-0328HTag:GST
Source (Host):Insect CellSpecies:Human
Product nameRecombinant Human CAMK2B Protein, GST-Tagged
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Cat.#:CAMK2B-0329HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CAMK2B Protein, GST-Tagged
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Cat.#:CAMK2B-2286HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CAMK2B Protein, MYC/DDK-tagged
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Cat.#:CAMK2B-10682HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CAMK2B, GST-tagged
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Cat.#:CAMK2B-156HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CAMK2B Protein, His-tagged
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Cat.#:CAMK2B-45HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CAMK2beta, GST-tagged
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Cat.#:CAMK2B-970HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CAMK2B, His & GST tagged
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Cat.#:CAMK2B-5867CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CAMK2B
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Cat.#:CAMK2B-265HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CAMK2B, His-tagged, Active
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Cat.#:CAMK2B-596HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CAMK2B cell lysate
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Involved Pathway

CAMK2B involved in several pathways and played different roles in them. We selected most pathways CAMK2B participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ErbB signaling pathway
PIK3R2; CAMK2G; KRAS; GRB2A; ERBB2; MAP2K4B; HRAS; PIK3R5; PLCG2; NRG1
Calcium signaling pathway
ORAI3; CACNA1SB; SLC8A1; CALM3; GNAL; HRH2; AVPR1B; PLCB1; CD38; TRHRB
cAMP signaling pathway
VIPR2; CALML3; CALM1; PLCE1; GRIA3; VAV1; CNGA2; RHOA; RAF1; CAMK2A
HIF- signaling pathway
HK2; PDK1; RPS6; TCEB1; IGF1R; TLR4; PIK3R1; TIMP1; INS; IFNG
Oocyte meiosis
PPP2R1B; MAPK12B; PPP3CC; PPP2R1A; INS; ANAPC5; CAMK2B; PPP3R2; YWHABL; IGF1
Adrenergic signaling in cardiomyocytes
VMHC; GNA15.1; AGTR1; CACNB1; ATP1A2A; PPP2R2CA; PPP1CC; CALML5; CACNA1SB; ATP1A1B
Wnt signaling pathway
FZD8A; FZD7B; CAMK2B1; ROCK2A; PRKACAB; NKD2B; MMP7; PPP3CCB; NLK2; RBX1
Circadian entrainment
GRIA4; CAMK2D; GRIN1; NOS1; ITPR1; PRKACB; MTNR1A; RYR3; MTNR1B; GRIN2D
Long-term potentiation
PRKCG; CALM3; PLCB2; GRIN2A; RAP1A; PLCB4; PLCB1; ITPR1; CAMK2G; EP300
Neurotrophin signaling pathway
RAP1B; ARHGDIB; MAPK11; GRB2; NGF; GSK3B; SHC4; PSEN1; ZFP110; PIK3CA
Cholinergic synapse
PIK3R3; ITPR1; PRKCG; MAPK3; GNAQ; CAMK2D; GNG4; KCNQ4; GNG7; SLC5A7
Dopaminergic synapse
DRD1A; DRD1; DRD4; PPP2CA; ATF4; DDC; CLOCK; CALML3; CREB5; AKT2
Olfactory transduction
OLFR497; OLFR473; OLFR49; OR2F1; OLFR154; OLFR507; OLFR470; OLFR1440; OR5H1; OR10C1
Inflammatory mediator regulation of TRP channels
ACCN3; CYP2C55; CYP4A14; TRPA1; PIK3R1; PRKACB; PIK3R2; CYP2J5; HTR2A; PRKACA
Insulin secretion
ATP1A2; KCNMB1; FXYD2; INS; KCNMA1; GIP; INS1; ADCYAP1; INS2; PRKCG
GnRH signaling pathway
MAP3K1; GNAS; ATF4B1; RAF1A; GNA11; MAPK11; CALML5; PTK2B; MAPK12; PLA2G4A
Melanogenesis
FZD6; WNT11; FZD8B; FZD9; ADCY1B; PRKACA; POMCA; MAPK1; TYRP1B; WNT16
Oxytocin signaling pathway
MAP2K1; CALML3; GNAI3; PPP3R1; FOS; CACNA2D4; OXTR; PTGS2; PRKAB2; CAMK1G
Glucagon signaling pathway
LDHAL6A; PRKAA2; CALM1; PFKFB1; PDHB; PKM; AKT2; ITPR3; CREB3L1; SIK2
Aldosterone synthesis and secretion
CALM4; SCARB1; AGTR1; CAMK2A; GNAQ; KCNK3; CAMK1G; PLCB2; ATF6B; PRKD3
Gastric acid secretion
KCNJ2; SST; SLC9A1; CALM3; EZR; KCNK2; CALM2; Car2; GNAI3; PLCB2
Amphetamine addiction
PRKCG; GRIN1; TH; CALM4; GRIA4; GRIN3B; ATF6B; FOSB; CREB3L4; MAOA
Tuberculosis
RAB5C; RFXANK; BAX; LSP1; PPP3R1; KSR1; CD209A; IFNA5; TLR4; STAT1
Proteoglycans in cancer
ARAF; WNT16; MSN; MMP9; ANK1; LUM; SDC1; ERBB2; PRKACB; GRB2
Glioma
CAMK2G; TGFA; SHC4; SHC1; SOS1; CALM2; CCND1; CALML3; PIK3CB; TP53

Protein Function

CAMK2B has several biochemical functions, for example, ATP binding, actin binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK2B itself. We selected most functions CAMK2B had, and list some proteins which have the same functions with CAMK2B. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein HSPA13; RET; ABCB9; ACTG2; MAP2K4A; MASTL; HSPA9; PHKG1A; NME2A; MAP4K2
Function actin binding
Related Protein FXYD5; SPATA31; IPP; ARPC1A; MYO1F; DBNLA; CYFIP1; CCR5; ACTR2A; MYH9A
Function calmodulin binding
Related Protein MYH3; ORAI1; MYH1; MARCKSL1A; MAPKAPK2B; MYO5C; RYR3; INVS; CAMK1; REM1
Function calmodulin-dependent protein kinase activity
Related Protein CAMKK2; CAMK2A; DCX; CAMK2D1; CAMK2D2; CAMK1GA; MAPKAPK5; CAMK1GB; MYLK3; DAPK1
Function protein binding
Related Protein BASP1; G3BP2; BEND5; PRDM1; FAM65B; BANK1; TTI1; DDA1; CCDC170; EIF5B
Function protein homodimerization activity
Related Protein VIL1; NKX2; ODC1; FOXP3; AGR2; Il6ra; SERPINF2; ACOT7; NRBP1; TREX1

Interacting Protein

CAMK2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK2B here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK2B.
b3kwq7_human; 146664; ACOT7; RBFOX2; KRTAP10-11; RAP2B; RPL11