clec1b
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  • Official Full Name
  • C-type lectin domain family 1, member b
  • Background
  • Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM;602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and;either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in;myeloid cells and NK cells (Colonna et al., 2000 (PubMed 10671229)).
  • Synonyms
  • CLEC1B; C-type lectin domain family 1, member b; C-type lectin domain family 1 member B; 1810061I13Rik; C type lectin domain family 1 member B; C type lectin like receptor 2; C-type lectin-like receptor 2; C-type lectin-like receptor-2; CLC1B_HUMAN; CLEC 2; CLEC 2B; CLEC-2; CLEC2; CLEC2B; PRO1384; QDED721; OTTMUSP00000033486; OTTMUSP00000033487
Cat.#:CLEC1B-1460HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CLEC1B Protein, GST-tagged
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Cat.#:CLEC1B-11311HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLEC1B, GST-tagged
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Cat.#:CLEC1B-23HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CLEC1B protein, His-tagged
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Cat.#:CLEC1B-279HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CLEC1B, His-tagged
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Cat.#:CLEC1B-6911HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLEC1B, His tagged
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Cat.#:CLEC1B-3552MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CLEC1B Protein
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Cat.#:Clec1b-858MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Clec1b Protein, Fc-tagged
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Cat.#:CLEC1B-904RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CLEC1B Protein, His-tagged
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Cat.#:CLEC1B-1773HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLEC1B cell lysate
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Involved Pathway

CLEC1B involved in several pathways and played different roles in them. We selected most pathways CLEC1B participated on our site, such as GPVI-mediated activation cascade, Hemostasis, Platelet activation, signaling and aggregation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC1B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
GPVI-mediated activation cascade
RHOB; PIK3R6; LCP2A; G6b; PDPN; FCER1GL; RHOGA; C6orf25; CLEC1B
Hemostasis
GRB7; DOCK2; PROCA; KLC3; CD177; ITPK1; CFHL1; ANXA2; GAS6; KIF20A
Platelet activation, signaling and aggregation
CLU; ABHD6B; SCG3; C6orf25; SPARC; GNA13B; PDPN; G6b; F13A1A.1; BRPF3

Protein Function

CLEC1B has several biochemical functions, for example, carbohydrate binding, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC1B itself. We selected most functions CLEC1B had, and list some proteins which have the same functions with CLEC1B. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein SBP; MAN2C1; REG3G; PRG2; LMAN2; Siglece; HBL4; ATRNL1; ASGR1; CLEC14A
Function protein binding
Related Protein GTF3C5; DNALI1; HIST1H3F; SNX1; GSTO1; ARL6IP1; HYLS1; HEMGN; CACNB4; FAM125B
Function transmembrane signaling receptor activity
Related Protein GP1BB; KLRC1; NPR2; GPR182; KLRF1; EMR4; KIR2DS2; AGER; CD4; Cd79a, Cd79b

Interacting Protein

CLEC1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC1B.
NINL

CLEC1B Related Articles

Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
Noack, S; Seiffart, V; et al. Periostin Secreted by Mesenchymal Stem Cells Supports Tendon Formation in an Ectopic Mouse Model. STEM CELLS AND DEVELOPMENT 23:1844-1857(2014).