Recombinant Human CLEC1B protein, His-tagged

• Cat.No.: CLEC1B-23H
• Product Overview: Recombinant human CLEC1B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: CLEC1B, as known as C-type lectin domain family 1 member B, is a type 2 transmembrane glycoprotein and member of the C-type lectin-like family of receptors. This protein is expressed preferentially in liver, and is also detected in myeloid cells, platelets, and megakaryocytes. It has been reported that CLEC2/CLEC1B meditates powerful platelet aggregation by binding to the snake venom protein, rhodocytin and the molecule podoplanin.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 21.8kDa (184aa)
  28-57kDa (SDS-PAGE under reducing conditions.)
• AA Sequence: ADPSVMQRNY LQGENENRTG TLQQLAKRFC QYVVKQSELK GTFKGHKCSP CDTNWRYYGD SCYGFFRHNL TWEESKQYCT DMNATLLKID NRNIVEYIKA RTHLIRWVGL SRQKSNEVWK WEDGSVISEN MFEFLEDGKG NMNCAYFHNG KMHPTFCENK HYLMCERKAG MTKVDQLPHH HHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: CLEC1B C-type lectin domain family 1, member B [ Homo sapiens ]
• Official Symbol: CLEC1B
• Synonyms: CLEC1B; C-type lectin domain family 1 member B; CLEC2; CLEC-2; C-type lectin-like receptor 2; C-type lectin-like receptor-2; CLEC2B; PRO1384; QDED721
• Gene ID: 51266
• mRNA Refseq: NM_001099431
• Protein Refseq: NP_001092901
• MIM: 606783
• UniProt ID: Q9P126
• Chromosome Location: 12p13.31
• Function: protein binding; receptor activity; sugar binding; transmembrane signaling receptor activity