• Official Full Name
  • collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
  • Background
  • This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • COLQ; collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; acetylcholinesterase collagenic tail peptide; acetylcholinesterase associated collagen; AChE Q subunit; collagenic tail of endplate acetylcholinesterase; EAD; single strand of homotrimeric collagen like tail subunit of asymmetric acetylcholinesterase; Acetylcholinesterase collagen-like tail subunit isoform I; Acetylcholinesterase collagenic tail peptide precursor; Acetylcholinesterase-associated collagen; asymmetric acetylcholinesterase; COLQ_HUMAN; single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human COLQ Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse COLQ Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat COLQ Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Colq, His-tagged

Protein Function

COLQ has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COLQ itself. We selected most functions COLQ had, and list some proteins which have the same functions with COLQ. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein ELP4; ARL14; TPM3; AQP5; FKBP6; RAP1B; FIP1L1; POLR1D; TMPRSS7; CDC23

COLQ Related Articles

Katarzyna, MZ; Belaya, K; et al. Collagen Q - A potential target for autoantibodies in myasthenia gravis. JOURNAL OF THE NEUROLOGICAL SCIENCES 348:241-244(2015).
Ohno, K; Ito, M; et al. Collagen Q is a Key Player for Developing Rational Therapy for Congenital Myasthenia and for Dissecting the Mechanisms of Anti-MuSK Myasthenia Gravis. JOURNAL OF MOLECULAR NEUROSCIENCE 53:359-361(2014).