cryz
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  • Official Full Name
  • crystallin, zeta (quinone reductase)
  • Background
  • Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.
  • Synonyms
  • CRYZ; crystallin, zeta (quinone reductase); quinone oxidoreductase; NADPH:quinone reductase; Zeta crystallin; Crystallin zeta (quinone reductase); Crystallin zeta; DKFZp779E0834; FLJ41475; MS766; QOR_HUMAN; Zeta-crystallin; OTTHUMP00000011194; OTTHUMP00000011210; OTTHUMP00000011211; OTTHUMP00000011213
Cat.#:CRYZ-1947HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CRYZ Protein, GST-tagged
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Cat.#:CRYZ-257HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRYZ, His-tagged
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Cat.#:CRYZ-3952MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CRYZ Protein
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Cat.#:CRYZ-1624RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CRYZ Protein
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Cat.#:CRYZ-1048RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CRYZ Protein, His-tagged
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Cat.#:CRYZ-3595CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CRYZ
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Cat.#:CRYZ-5788ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CRYZ
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Cat.#:CRYZ-408HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CRYZ cell lysate
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Protein Function

CRYZ has several biochemical functions, for example, NOT NADH binding, NADPH binding, NADPH:quinone reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CRYZ itself. We selected most functions CRYZ had, and list some proteins which have the same functions with CRYZ. You can find most of the proteins on our site.
Function
Related Protein
Function NOT NADH binding
Related Protein CRYZ
Function NADPH binding
Related Protein CBR4; CBR3; DHFR; GRHPR; CRYZ; MTRR; HMGCR; QDPR; FASN; KCNAB1
Function NADPH:quinone reductase activity
Related Protein TP53I3; ADH4; CRYZL1; CRYZ
Function mRNA 3-UTR binding
Related Protein CPEB4; RBM24A; CRYZ; CPEB1; RBM4; RBMS3; SECISBP2; ANGEL2; CARHSP1; YBX2
Function zinc ion binding
Related Protein MMP25; RNF40; RNF222; APOBEC3B; TRIM15; CALB1; RFWD2; ZDHHC9; UBR2; TET2

Interacting Protein

CRYZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRYZ here. Most of them are supplied by our site. Hope this information will be useful for your research of CRYZ.
MCC; IKBKE; ssrna_au; CSNK2A2; CBX5; Smek1; Ppp6r1; ASPM; ZNF526; Mad2l1bp; Cul3