• Official Full Name
  • exoribonuclease 1
  • Background
  • THEX1 (3'hExo) is a 3' exonuclease that may play a role in the degradation of histone mRNA transcripts. A recently identified member of the DEDDh 3 exonuclease family, THEX1 binds the conserved stem-loop structure found at the 3' end of mRNA in vitro. The
  • Synonyms
  • ERI1; exoribonuclease 1; 3-5 exoribonuclease 1; eri-1 homolog; 3-5 exonuclease ERI1; enhanced RNAi protein 1; histone mRNA 3-exonuclease 1; three prime histone mRNA exonuclease 1; histone mRNA 3 end-specific exonuclease; Thex1; eri-1; 3hexo; 3110010F15Rik
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ERI1, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ERI1 Protein
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Eri1 protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ERI1 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ERI1
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ERI1
Source (Host):Species:Human
Product nameRecombinant Human ERI1 293 Cell Lysate

Protein Function

ERI1 has several biochemical functions, for example, 3-5 exonuclease activity, 3-5-exoribonuclease activity, histone pre-mRNA stem-loop binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERI1 itself. We selected most functions ERI1 had, and list some proteins which have the same functions with ERI1. You can find most of the proteins on our site.
Related Protein
Function 3-5 exonuclease activity
Related Protein MRE11A; POLE; POLG; ERI1; EXD2; RAD1; RAD9B; REXO2; APLF; TREX1
Function 3-5-exoribonuclease activity
Related Protein TOE1; PNPT1; ERI1; SMFN; EXOSC7; ERI2; C16orf57; USB1; EXOSC3; CNOT8
Function histone pre-mRNA stem-loop binding
Related Protein ERI1; SLBP
Function metal ion binding
Related Protein MOXD2; KAT8; ZNRF3; TGM2A; ZNF16; ZFP628; ZNF483; ENDOU2; ZBTB39; ZNF384L
Function rRNA binding
Related Protein RPS11; RPL12; MTERFD2; RPS4X; NOL12; MRPS17; DDX21; FASTKD2; RPL9; RPF2
Function ribosome binding
Related Protein CPEB2; CPEB1; EFTUD1; C12orf65; ETF1B; EIF2S1B; RPN2; HSPA5; SEC61A1; ERI1

Interacting Protein

ERI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERI1.
ssrna_cg; SYN1; Eif3a; Eif3e; Ppp2ca; Cep78; Naa50; Topbp1; Cdc16; CDCA5; CEP170P1

ERI1 Related Articles

Zhang, QF; Siegel, TN; et al. Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria. NATURE 513:431-+(2014).
Shimoyama, Y; Morikawa, Y; et al. Identification of human SEP1 as a glial cell line-derived neurotrophic factor-inducible protein and its expression in the nervous system. NEUROSCIENCE 121:899-906(2003).