• Official Full Name
  • ER lipid raft associated 2
  • Background
  • Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene.
  • Synonyms
  • ERLIN2; ER lipid raft associated 2; C8orf2, chromosome 8 open reading frame 2 , Erlin 2, SPFH domain family, member 2 , SPFH2; erlin-2; NET32; SPFH domain family, member 2; endoplasmic reticulum lipid raft-associated protein 2; stomatin-prohibitin-floti
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ERLIN2 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ER lipid raft associated 2, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ERLIN2 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ERLIN2 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ERLIN2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ERLIN2
Source (Host):Species:Human
Product nameRecombinant Human ERLIN2 293 Cell Lysate

Protein Function

ERLIN2 has several biochemical functions, for example, cholesterol binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERLIN2 itself. We selected most functions ERLIN2 had, and list some proteins which have the same functions with ERLIN2. You can find most of the proteins on our site.
Related Protein
Function cholesterol binding
Related Protein ABCG1; PMP2; PROM2; OSBPL5; SCP2; OSBP2; OSBPL3; APOA2; NPC1; NR1H3
Function protein binding
Related Protein NAA11; FGFBP1; RAB22A; PIANP; CAB39L; LDOC1; EEF1G; ATP6V1E1; CTBP1; FBXO9
Function ubiquitin protein ligase binding
Related Protein SLC22A18; UBE2W; CUL4B; CUL5A; EIF4E2; UCHL1; MAGEA2; HERC2; UBE2N; UBE2K

Interacting Protein

ERLIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERLIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERLIN2.
pi3p; 15-deoxy-delta(12,14; gcb; Ktn1; FN1; Rab5c; Bmpr1a; RAB7A; STK3; ICT1; Klhl21; Rmdn3; TMEM63B; P; Ufl1; C1qbp; Ppp6r3; NCSTN; HDAC11

ERLIN2 Related Articles

Dixit, G; Mikoryak, C; et al. Cholera toxin up-regulates endoplasmic reticulum proteins that correlate with sensitivity to the toxin. EXPERIMENTAL BIOLOGY AND MEDICINE 233:163-175(2008).
Shi, ST; Lee, KJ; et al. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that coffactionates with caveolin-2. JOURNAL OF VIROLOGY 77:4160-4168(2003).
Lee, H; Park, DS; et al. Src-induced phosphorylation of caveolin-2 on tyrosine 19 - Phospho-caveolin-2 (Tyr(P)(19)) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1. JOURNAL OF BIOLOGICAL CHEMISTRY 277:34556-34567(2002).