Recombinant Human ERLIN2 Protein, GST-tagged

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Recombinant Human ERLIN2 Protein, GST-tagged

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Cat.No. : ERLIN2-3479H
Product Overview : Human ERLIN2 full-length ORF ( NP_009106.1, 1 a.a. - 339 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 64.2 kDa
AA Sequence : MAQLGAVVAV ASSFFCASLF SAVHKIEEGH IGVYYRGGAL LTSTSGPGFH LMLPFITSYK SVQTTLQTDE VKNVPCGTSG GVMIYFDRIE VVNFLVPNAV YDIVKNYTAD YDKALIFNKI HHELNQFCSV HTLQEVYIEL FDQIDENLKL ALQQDLTSMA PGLVIQAVRV TKPNIPEAIR RNYELMESEK TKLLIAAQKQ KVVEKEAETE RKKALIEAEK VAQVAEITYG QKVMEKETEK KISEIEDAAF LAREKAKADA ECYTAMKIAE ANKLKLTPEY LQLMKYKAIA SNSKIYFGKD IPNMFMDSAG SVSKQFEGLA DKLSFGLEDE PLETATKEN
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ERLIN2 ER lipid raft associated 2 [ Homo sapiens ]
Official Symbol : ERLIN2
Synonyms : ERLIN2; ER lipid raft associated 2; C8orf2, chromosome 8 open reading frame 2 , Erlin 2, SPFH domain family, member 2 , SPFH2; erlin-2; NET32; SPFH domain family, member 2; endoplasmic reticulum lipid raft-associated protein 2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; SPFH2; SPG18; C8orf2; Erlin-2; MGC87072;
Gene ID : 11160
mRNA Refseq : NM_001003790
Protein Refseq : NP_001003790
MIM : 611605
UniProt ID : O94905

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