fads1
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  • Official Full Name
  • fatty acid desaturase 1
  • Background
  • The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
  • Synonyms
  • FADS1; fatty acid desaturase 1; LLCDL1; D5D; delta 5 desaturase; FADS6; FADSD5; TU12; delta-5 desaturase; delta(5) desaturase; delta-5 fatty acid desaturase; delta(5) fatty acid desaturase; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1; FLJ38956; F
Cat.#:FADS1-12639HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FADS1, GST-tagged
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Cat.#:FADS1-28816THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human FADS1
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Cat.#:FADS1-28817HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FADS1 protein, GST-tagged
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Cat.#:FADS1-781HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human FADS1
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Cat.#:FADS1-5431MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FADS1 Protein
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Cat.#:FADS1-2192RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FADS1 Protein
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Cat.#:FADS1-6472HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FADS1 293 Cell Lysate
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Involved Pathway

FADS1 involved in several pathways and played different roles in them. We selected most pathways FADS1 participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FADS1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Biosynthesis of unsaturated fatty acids
Scd2; ELOVL5; HADHAB; PECR; ELOVL2; SCDB; ACOX1; TECRB; TECR; ACOT5
Fatty acid metabolism
ACSBG2; ACSL1; CPT1C; ACOX1; SCD5; ACACA; TECRB; FADS2; CPT2; ACADVL

Protein Function

FADS1 has several biochemical functions, for example, C-5 sterol desaturase activity, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FADS1 itself. We selected most functions FADS1 had, and list some proteins which have the same functions with FADS1. You can find most of the proteins on our site.
Function
Related Protein
Function C-5 sterol desaturase activity
Related Protein FADS1; SC5DL
Function oxidoreductase activity
Related Protein CYP4A14; UOX; AOX3L1; HIBADHA; CYP2AD3; ERO1L; ALDH2.2; CYP3A41B; ALDH9A1A.2; CYP2AA9

Interacting Protein

FADS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FADS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FADS1.
q65zq1_human; PAAF1; DHCR7; CCDC22