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FOXI1

Official Full Name

forkhead box I1
Overview

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms

FOXI1; forkhead box I1; forkhead box protein I1; forkhead homolog 10; HNF-3/forkhead homolog 3; Hfh3; Fkh10; HFH-3; FREAC6; 5830401E05Rik;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FOXI1-513H	Recombinant Human FOXI1	Mammalian Cell	His		Inquiry
Human	FOXI1-6155HCL	Recombinant Human FOXI1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	FOXI1-2564H	Recombinant Human FOXI1 Protein, His-tagged	E.coli	His		Inquiry
Human	FOXI1-4454H	Recombinant Human FOXI1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FOXI1-4576H	Recombinant Human FOXI1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	FOXI1-2969H	Recombinant Human FOXI1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	FOXI1-5074HF	Recombinant Full Length Human FOXI1 Protein, GST-tagged	In Vitro Cell Free System	GST	283 amino acids	Inquiry
Human	FOXI1-2969H-B	Recombinant Human FOXI1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Foxi1-1520M	Recombinant Mouse Foxi1 Protein, His-tagged	E.coli	N-His	Met1-Asp173	Inquiry
Mouse	Foxi1-3072M	Recombinant Mouse Foxi1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	FOXI1-9633Z	Recombinant Zebrafish FOXI1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
FOXI1 Related Articles

FOXI1 involved in several pathways and played different roles in them. We selected most pathways FOXI1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FOXI1 has several biochemical functions, for example, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXI1 itself. We selected most functions FOXI1 had, and list some proteins which have the same functions with FOXI1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding, bending	TERF1;HMGB1;HMGA2;FOXL1;FOXD1;SRY;HMGB3;GATA1;TOP2A
RNA polymerase II core promoter proximal region sequence-specific DNA binding	TCF4;GMEB1;ESR1;HAND1;NOBOX;NEUROD6;CREB3;SFPI1;AEBP2
sequence-specific DNA binding	CREB5;TBX3;CLOCK;LBX1;DLX1A;ZNF711;TAF2;HOXB9A;CSRNP1
transcription factor activity, sequence-specific DNA binding	BRD8;TFAM;ZNF548;SIX4;ZNF193;SIX1;TARDBP;ZNF334;HOXD10
transcription regulatory region DNA binding	PAX8;KLF2A;ZNF831;HINFP;HMGB2;HNRNPL;PAX2;CBX4;NKX3
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	MEIS1;SOX12;MEF2B;ZNF750;NFIA;PPARA;FOXD1;STAT3;TFAM

FOXI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXI1.

Zhang, H; Wang, XL; et al. Time Point-Based Integrative Analyses of Deep-Transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw. STEM CELLS 33:806-818(2015).

Roy, A; Al-Bataineh, MM; et al. Collecting Duct Intercalated Cell Function and Regulation. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 10:305-324(2015).