GATA1

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GATA1

Official Full Name GATA binding protein 1 (globin transcription factor 1)
Background This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008]
Synonyms GATA1; GATA binding protein 1 (globin transcription factor 1); GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1; erythroid transcription factor; GATA-binding factor 1; NF-E1 DNA-binding protein; transcription factor GATA1; nuclear factor, erythroid 1; globin transcription factor 1; erythroid transcription factor 1;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GATA1-140H Recombinant Human GATA1 Protein, His-tagged E.coli His
    Human GATA1-2052H Recombinant Human GATA1, GST-tagged Wheat Germ GST
    Human GATA1-28476TH Recombinant Human GATA1, His-tagged E.coli His
    Human GATA1-689HCL Recombinant Human GATA1 cell lysate N/A
    Mouse Gata1-474M Recombinant Mouse Gata1 Protein, His-tagged E.coli His
    Mouse GATA1-6222M Recombinant Mouse GATA1 Protein Mammalian Cell His
    Rat GATA1-2481R Recombinant Rat GATA1 Protein Mammalian Cell His
    Rat Gata1-475R Recombinant Rat Gata1 Protein, His-tagged E.coli His
    Chicken GATA1-7013C Recombinant Chicken GATA1 Mammalian Cell His

    GATA1 involved in several pathways and played different roles in them. We selected most pathways GATA1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network SKI; MYB; YEATS4; MYOD1; CSF1R; CEBPB; PRTN3; CDK6; TOM1; GATA1
    Factors involved in megakaryocyte development and platelet production KIF20A; KIF3C; BA1; MAFGB; GATA6; BA1L; AKAP1B; H3F3D; HBG1; D-AKAP2
    Hemostasis CD9A; CENPE; ITPK1; HBG2; GATA1A; SLC3A2B; CABLES2; CFHL1; HBD; STXBP3
    IL-3 Signaling Pathway CISH; KCNIP3; SPI1B; BIRC5A; GNB2L1; GSK3AB; GATA1A; GATA2; PILRB; GATA1
    Notch-mediated HES/HEY network BGLAP; MYB; HES6; YY1; RCAN1; HEY1; GATA6; MYOD1; TLE1; GATA1
    Signaling events mediated by HDAC Class I GATA1; MXD1; SIRT4; FKBP3; PRMT5; SIRT2; SIRT5; SIRT7; GATA2; WDR77
    Signaling events mediated by HDAC Class II BCOR; ANKRA2; GATA1

    GATA1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA1 itself. We selected most functions GATA1 had, and list some proteins which have the same functions with GATA1. You can find most of the proteins on our site.

    Function Related Protein
    C2H2 zinc finger domain binding EHMT1; LEF1; TAF9; U2AF2; EHMT2; WT1; GATA1; EBF1; HMGA2; GATA2
    DNA binding CDT1; E2F5; LIN28A; ZBED3; HOXB8A; KCNIP3; GM6026; PPARG; SOX1A; HOXD12A
    DNA binding, bending HMGA2; TOP2B; TFAM; HMGB2; SRY; HHEX; FOXD1; CRIP1; FOXL1; FOXD4
    RNA polymerase II core promoter proximal region sequence-specific DNA binding ZNF680; E2F4; ZNF562; MYOD1; MITF; TP73; OTX1; PGR; ZIC3; KLF5
    RNA polymerase II core promoter sequence-specific DNA binding SUZ12; MAZ; ZNF277; TRP53; SOX8; SP1; TCF7L2; TAL1; SFPI1; EGR1
    RNA polymerase II regulatory region sequence-specific DNA binding TFAP2C; NR1D1; ZBTB11; TBX5; RFX6; ZNF561; PLAGL1; ZNF792; GLIS1; AASS
    RNA polymerase II transcription factor binding TOX2; ZFPM2A; MTDH; ZGLP1; ZFPM1; GATA3; T; XBP1; MEF2A; ID4
    chromatin DNA binding HIST1H1D; PPARGC1A; RARA; ZIC2; ACTN4; APEX1; RUVBL2; WBP2; NKAP; GRHL1
    core promoter binding EP300; E2F7; IFI203; INSM1B; MYOD1; ELK4; HMGA2; NEUROG3; CRY1; ELK1
    enhancer sequence-specific DNA binding KLF7B; GATA3; YY1; TFAP2B; GATA2; TBX19; ISL1; GATA5; SOX9; GATA4
    p53 binding SETD7; KDM1A; HSPD1; ZNF385A; TRP63; TAF9; CHD8; PTTG1IP; RNF20; TRP53
    protein binding LARS; SYNE1; ERAP1; CALCOCO2; GPAA1; CRY1; TPP2; CACNA1SB; ALG2; IYD
    sequence-specific DNA binding VDRB; ZKSCAN4; ENG2A; NR2E1; ENG1A; JUNBB; SIX4B; TRP53; RXRA; RARGB
    transcription factor activity, sequence-specific DNA binding HOXC8A; IRF6; ZNF286A; GTF2IRD1; ZNF792; TEFB; FOXO3B; ARNT2; TP63; SLC25A46
    transcription regulatory region sequence-specific DNA binding NFE2L2B; SUV39H1; SOX2; NR5A2; DDIT3; NFE2L2A; EPAS1B; ARNTL; NR5A1B; CRY2
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding FOSL1; SOX12; NUCKS1; GLIS2; FOXI1; EBF2; TFAP2B; SFPI1; PLSCR1; GATA1
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding MAFBB; MYF6; DLX2; MAFGB; MAFG; CREB3L3; GLIS1; SOHLH2; HSF2; RAD21
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding TGIF1; CUX2; SP3; SNAI1; ETS2; CREBBP; PROX1B; CC2D1B; REST; SNAI2
    zinc ion binding RNF181; RNF112; TRIM29; LHX2; CPXM1; CA1; ZRANB2; ADAM28; CPA5; DTX3

    GATA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA1.

    FRS3; PRKAB2; HOXA1; KRTAP10-5; CCDC24; FBF1; RADIL

    Wang, KP; Zhao, LQ; et al. Differential co-expression analysis of rheumatoid arthritis with microarray data. MOLECULAR MEDICINE REPORTS 10:2421-2426(2014).
    Battista, JM; Tallmadge, RL; et al. Hematopoiesis in the equine fetal liver suggests immune preparedness. IMMUNOGENETICS 66:635-649(2014).

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