• Official Full Name
  • gem (nuclear organelle) associated protein 5
  • Background
  • This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  • Synonyms
  • GEMIN5; gem (nuclear organelle) associated protein 5; GEMIN-5; gem-associated protein 5;
Source (Host):HEK293Species:Human
Product nameRecombinant Human GEMIN5 Protein, MYC/DDK-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GEMIN5 Protein, GST-tagged

GEMIN5 Related Articles

Fernandez-Chamorro, J; Pineiro, D; et al. Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation. NUCLEIC ACIDS RESEARCH 42:5742-5754(2014).
Borg, R; Cauchi, RJ; et al. The Gemin Associates of Survival Motor Neuron Are Required for Motor Function in Drosophila. PLOS ONE 8:-(2013).