• Official Full Name
  • G protein-coupled estrogen receptor 1
  • Background
  • This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
  • Synonyms
  • GPER; G protein-coupled estrogen receptor 1; CMKRL2, G protein coupled receptor 30 , GPR30; G-protein coupled estrogen receptor 1; CEPR; DRY12; FEG 1; GPCR Br; LERGU; LERGU2; LyGPR; mER; heptahelix receptor; chemokine receptor-like 2; IL8-related recepto
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GPER Protein
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GPER Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GPER Protein

GPER Related Articles

Chourasia, TK; Pang, YF; et al. The Catecholestrogen, 2-Hydroxyestradiol-17beta, Acts as a G Protein-Coupled Estrogen Receptor 1 (GPER/GPR30) Antagonist to Promote the Resumption of Meiosis in Zebrafish Oocytes. BIOLOGY OF REPRODUCTION 92:-(2015).
Li, YR; Ren, CE; et al. Expression of G protein estrogen receptor (GPER) on membrane of mouse oocytes during maturation. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 30:227-232(2013).