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HPS3

  • Official Full Name

    Hermansky-Pudlak syndrome 3

  • Overview

    This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.
  • Synonyms

    HPS3; Hermansky-Pudlak syndrome 3; Hermansky-Pudlak syndrome 3 protein; SUTAL; Cocoa; DKFZp686F0413; FLJ22704; Hermansky Pudlak syndrome 3; Hermansky Pudlak syndrome 3 protein;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HPS3-5015H Recombinant Human HPS3 Protein, GST-tagged Wheat Germ GST
Human HPS3-13926H Recombinant Human HPS3, GST-tagged E.coli GST C-term-418a.a.
Human HPS3-5396HCL Recombinant Human HPS3 293 Cell Lysate HEK293 N/A
Human HPS3-3630HF Recombinant Full Length Human HPS3 Protein, GST-tagged In Vitro Cell Free System GST 372 amino acids
Zebrafish HPS3-7790Z Recombinant Zebrafish HPS3 Mammalian Cell His
  • HPS3 Related Articles

HPS3 involved in several pathways and played different roles in them. We selected most pathways HPS3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HPS3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HPS3 itself. We selected most functions HPS3 had, and list some proteins which have the same functions with HPS3. You can find most of the proteins on our site.

Function Related Protein

HPS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS3.

Gimelli, G; Giorda, R; et al. A large analphoid invdup(3)(q22.3qter) marker chromosome characterized by array-CGH in a child with malformations, mental retardation, ambiguous genitalia and Blaschko's lines. EUROPEAN JOURNAL OF MEDICAL GENETICS 50:264-273(2007).
Helip-Wooley, A; Westbroek, W; et al. Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. BMC CELL BIOLOGY 6:-(2005).
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