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HSP90AB1

  • Official Full Name

    heat shock protein 90kDa alpha (cytosolic), class B member 1

  • Overview

    HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,;protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play;important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.;There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive;form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM;606219) (Chen et al., 2005 (PubMed 16269234)).
  • Synonyms

    HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock 90kD protein 1, beta , heat shock 90kDa protein 1, beta , HSPC2, HSPCB; heat shock protein HSP 90-beta; heat shock 84 kDa; heat shock protein beta; heat shock 90kD protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSP90AB1-135H Recombinant Human HSP90AB1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSP90AB1-1562H Recombinant Human HSP90AB1 protein E.coli N/A
Human HSP90AB1-4924H Recombinant Human Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 1 Sf9 Insect Cell N/A
Human HSP90AB1-49H Recombinant Human HSP90AB1, His-tagged E.coli His
Human HSP90AB1-29404TH Recombinant Human HSP90AB1 N/A
Human HSP90AB1-13979H Recombinant Human HSP90AB1, GST-tagged E.coli GST 326-710a.a.
Human HSP90AB1-29405TH Recombinant Human HSP90AB1 N/A
Human HSP90AB1-1462H Recombinant Human HSP90AB1, His-tagged Sf9 Insect Cell His
Human HSP90AB1-5100H Recombinant Human HSP90AB1 Protein, GST-tagged Wheat Germ GST
Human HSP90AB1-5361HCL Recombinant Human HSP90AB1 293 Cell Lysate HEK293 N/A
Human HSP90AB1-071H Active Recombinant Human HSP90AB1 Protein, His-tagged E. coli His 2-724
Human HSP90AB1-3056H Recombinant Human HSP90AB1 protein, His&Myc-tagged E.coli His&Myc 2-724aa
Human HSP90AB1-1114H Recombinant Human HSP90AB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HSP90AB1-016H Active Recombinant Human HSP90AB1 Protein, His-tagged E.coli His 2-724
Human HSP90AB1-048H Recombinant Human HSP90AB1 Protein, N-His-tagged E.coli N-His 803
Human HSP90AB1-681HFL Recombinant Full Length Human HSP90AB1 Protein, C-Flag-tagged Mammalian cells Flag
Human HSP90AB1-3471H Recombinant Human HSP90AB1 Protein (Met1-Asp724), His tagged E.coli His Met1-Asp724
Human HSP90AB1-3859H Recombinant Human HSP90AB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSP90AB1-1114H-B Recombinant Human HSP90AB1 Protein Pre-coupled Magnetic Beads HEK293
Human HSP90AB1-3592H Recombinant Human HSP90AB1 protein, His-tagged E.coli His 330-710 aa
Human HSP90AB1-3808HF Recombinant Full Length Human HSP90AB1 Protein, GST-tagged In Vitro Cell Free System GST 724 amino acids
Mouse HSP90AB1-7898M Recombinant Mouse HSP90AB1 Protein Mammalian Cell His
Mouse Hsp90ab1-1189M Recombinant Mouse Hsp90ab1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HSP90AB1-4350M Recombinant Mouse HSP90AB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSP90AB1-4350M-B Recombinant Mouse HSP90AB1 Protein Pre-coupled Magnetic Beads HEK293
Rat HSP90AB1-2940R Recombinant Rat HSP90AB1 Protein Mammalian Cell His
Rat HSP90AB1-2595R-B Recombinant Rat HSP90AB1 Protein Pre-coupled Magnetic Beads HEK293
Rat HSP90AB1-2595R Recombinant Rat HSP90AB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cattle HSP90AB1-2723C Recombinant Cattle HSP90AB1 Protein, His-tagged E.coli N-His Met1-Asp724
Rhesus Macaque HSP90AB1-2161R Recombinant Rhesus monkey HSP90AB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSP90AB1-1982R Recombinant Rhesus Macaque HSP90AB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSP90AB1-1982R-B Recombinant Rhesus Macaque HSP90AB1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HSP90AB1-8897Z Recombinant Zebrafish HSP90AB1 Mammalian Cell His
Chicken HSP90AB1-7098C Recombinant Chicken HSP90AB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSP90AB1 Related Articles

HSP90AB1 involved in several pathways and played different roles in them. We selected most pathways HSP90AB1 participated on our site, such as Protein processing in endoplasmic reticulum, PIK-Akt signaling pathway, Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSP90AB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumUBQLN1;LMAN1;HERPUD1;NFE2L2A;CAPN1;SEC24C;SELS;DNAJC5;UBE2D3
PIK-Akt signaling pathwayPIK3R3;PPP2R3C;RELA;IFNAR1;MAPK3;ITGB6;FGF1;GNG7;TEK
Antigen processing and presentationLGMN;TAP1;KIR2DS2;PSME2;RFXANK;HLA-DRB4;CD4;KLRC3;HSPA1L
NOD-like receptor signaling pathwayCcl12;TAB2;NLRP1;IL8L1;MAPK12A;CARD8;RIPK2;IL-8;IKBKG
Progesterone-mediated oocyte maturationCPEB1;CDK1;MAD2L2;FZR1A;RPS6KA1;CDC26;CDC25C;FZR1;RAF1A
Estrogen signaling pathwayGPR30;CALML3;HSP90AB1;PIK3CG;GNAQ;CALM3;MAP2K2;GNAI3;HSPA6
Pathways in cancerVEGFC;LAMA4;PTEN;PRKACB;PLEKHG5;FGF7;Pdgfa&Pdgfb;PRKCA;SMO
Prostate cancerMTOR;ERBB2;INS1;PIK3CG;ACTL6B;TGFA;HSP90B1;NDRG1;PIK3R3

HSP90AB1 has several biochemical functions, for example, ATP binding, CTP binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSP90AB1 itself. We selected most functions HSP90AB1 had, and list some proteins which have the same functions with HSP90AB1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingBMPR1AA;MYH1E;NLRC5;ATP1A1A.3;MAP4K2;EPHA10;WEE2;AK8;P2RX5
CTP binding
GTP bindingNME1;RAB15;RAB14;SEPT7;TUBD1;IRGF1;RRAS2;SEPT7A;ARL5C
MHC class II protein complex bindingHSP90AB1;MS4A1;HLA-DMB;HSPA8;ATP1B1;HLA-DOB;HLA-DMA;YWHAE;PKM2
TPR domain bindingPDE2A;RAB8B;STUB1;HSP90AA1;HSP90AB1
UTP bindingMTPAP;HSP90AB1
dATP bindingST13;HSP90AB1;ERCC3
double-stranded RNA bindingZFP346;ILF3;RFTN1;MSN;OASL1;OAS1;TARBP2;OASL;ILF2
ion channel bindingYWHAQ;CHERP;HOMER1;SUMO1;FAM115A;CAV1;LRRK2;CIB1;DIAP1
kinase bindingCEBPB;CDC37;PARK2;DUSP12;HAP1;CEBPA;TNFAIP3;MOBKL1A;CHP
nitric-oxide synthase regulator activityCALM1;CALM3;AKT1;HSP90AA1.1;HSP90AA1;ESR1;CALM2;HSP90AB1
poly(A) RNA bindingPARP1;CPEB4;YTHDF3;IMP3;STRAP;MYH9;FASTKD5;CCDC55;MRPS12
protein bindingSPHK2;C1QTNF3;MYOC;POU2AF1;LSM6;LGALS14;RCN1;EDC4;HDAC1
protein kinase bindingAP2A2;KIF20A;USP37;BORA;KCNH1;CENPJ;VRK1;PIH1D1;TPCN2
sulfonylurea receptor bindingKCNJ8;HSP90AB1
unfolded protein bindingCALR3;GRPEL1;AHSP;DNAJA2L;CCT5;DNAJB1A;MKKS;ERO1LB;CDC37L1

HSP90AB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSP90AB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSP90AB1.

EGFR; CDC37; CDC37L1

Sun, Y; Biscarini, F; et al. Genetic parameters and across-line SNP associations differ for natural antibody isotypes IgM and IgG in laying hens. ANIMAL GENETICS 44:413-424(2013).
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