Recombinant Human HSP90AB1 Protein, GST-tagged

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Recombinant Human HSP90AB1 Protein, GST-tagged

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Cat.No. : HSP90AB1-5100H
Product Overview : Human HSP90AB1 full-length ORF ( NP_031381.2, 1 a.a. - 724 a.a.) recombinant protein with GST-tag at N-terminal.
Description : HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 109.7 kDa
AA Sequence : MPEEVHHGEE EVETFAFQAE IAQLMSLIIN TFYSNKEIFL RELISNASDA LDKIRYESLT DPSKLDSGKE LKIDIIPNPQ ERTLTLVDTG IGMTKADLIN NLGTIAKSGT KAFMEALQAG ADISMIGQFG VGFYSAYLVA EKVVVITKHN DDEQYAWESS AGGSFTVRAD HGEPIGRGTK VILHLKEDQT EYLEERRVKE VVKKHSQFIG YPITLYLEKE REKEISDDEA EEEKGEKEEE DKDDEEKPKI EDVGSDEEDD SGKDKKKKTK KIKEKYIDQE ELNKTKPIWT RNPDDITQEE YGEFYKSLTN DWEDHLAVKH FSVEGQLEFR ALLFIPRRAP FDLFENKKKK NNIKLYVRRV FIMDSCDELI PEYLNFIRGV VDSEDLPLNI SREMLQQSKI LKVIRKNIVK KCLELFSELA EDKENYKKFY EAFSKNLKLG IHEDSTNRRR LSELLRYHTS QSGDEMTSLS EYVSRMKETQ KSIYYITGES KEQVANSAFV ERVRKRGFEV VYMTEPIDEY CVQQLKEFDG KSLVSVTKEG LELPEDEEEK KKMEESKAKF ENLCKLMKEI LDKKVEKVTI SNRLVSSPCC IVTSTYGWTA NMERIMKAQA LRDNSTMGYM MAKKHLEINP DHPIVETLRQ KAEADKNDKA VKDLVVLLFE TALLSSGFSL EDPQTHSNRI YRMIKLGLGI DEDEVAAEEP NAAVPDEIPP LEGDEDASRM EEVD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 [ Homo sapiens ]
Official Symbol : HSP90AB1
Synonyms : HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock 90kD protein 1, beta , heat shock 90kDa protein 1, beta , HSPC2, HSPCB; heat shock protein HSP 90-beta; heat shock 84 kDa; heat shock protein beta; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; 90-kda heat shock protein beta HSP90 beta; HSP84; HSPC2; HSPCB; D6S182; HSP90B; HSP90-BETA; FLJ26984;
Gene ID : 3326
mRNA Refseq : NM_007355
Protein Refseq : NP_031381
MIM : 140572
UniProt ID : P08238

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