Recombinant Full Length Human HSP90AB1 Protein, C-Flag-tagged

• Cat.No.: HSP90AB1-681HFL
• Product Overview: Recombinant Full Length Human HSP90AB1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 83.1 kDa
• AA Sequence: MPEEVHHGEEEVETFAFQAEIAQLM SLIINTFYSNKEIFLRELISNASDA LDKIRYESLTDPSKLDSGKE LKIDIIPNPQERTLTLVDTGIGMTK ADLINNLGTIAKSGTKAFMEALQAG ADISMIGQFGVGFYSAYLVA EKVVVITKHNDDEQYAWESSAGGSF TVRADHGEPIGRGTKVILHLKEDQT EYLEERRVKEVVKKHSQFIG YPITLYLEKEREKEISDDEAEEEKG EKEEEDKDDEEKPKIEDVGSDEEDD SGKDKKKKTKKIKEKYIDQE ELNKTKPIWTRNPDDITQEEYGEFY KSLTNDWEDHLAVKHFSVEGQLEFR ALLFIPRRAPFDLFENKKKK NNIKLYVRRVFIMDSCDELIPEYLN FIRGVVDSEDLPLNISREMLQQSKI LKVIRKNIVKKCLELFSELA EDKENYKKFYEAFSKNLKLGIHEDS TNRRRLSELLRYHTSQSGDEMTSLS EYVSRMKETQKSIYYITGES KEQVANSAFVERVRKRGFEVVYMTE PIDEYCVQQLKEFDGKSLVSVTKEG LELPEDEEEKKKMEESKAKF ENLCKLMKEILDKKVEKVTISNRLV SSPCCIVTSTYGWTANMERIMKAQA LRDNSTMGYMMAKKHLEINP DHPIVETLRQKAEADKNDKAVKDLV VLLFETALLSSGFSLEDPQTHSNRI YRMIKLGLGIDEDEVAAEEP
  NAAVPDEIPPLEGDEDASRMEEVDT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

Gene Information

• Gene Name: HSP90AB1 heat shock protein 90 alpha family class B member 1 [ Homo sapiens (human) ]
• Official Symbol: HSP90AB1
• Synonyms: HSP84; HSPC2; HSPCB; D6S182; HSP90B
• Gene ID: 3326
• mRNA Refseq: NM_007355.4
• Protein Refseq: NP_031381.2
• MIM: 140572
• UniProt ID: P08238