ifna16
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  • Official Full Name
  • interferon, alpha 16
  • Background
  • Interferon alpha-10 is a protein that in humans is encoded by the IFNA16 gene.
  • Synonyms
  • IFNA16; interferon, alpha 16; interferon alpha-16; IFN alphaO; IFN alpha N protein; Interferon alpha WA; IFN-alpha-16; IFN-alpha-N-protein; interferon alpha-WA; IFN-alphaO
Cat.#:IFNA16-46HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 16
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Cat.#:IFNA16-836HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFNA16 cell lysate
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Involved Pathway

IFNA16 involved in several pathways and played different roles in them. We selected most pathways IFNA16 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA16 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CCL15; LEPR; PRLR; IL-8; IL12A; IL15; IL7; PRL2; KDRL; CCL27B
Regulation of autophagy
IFNA17; INS; IFNA21; PRKAA1; PIK3R4; IFNA16; ULK3; ATG10; GABARAPL1; IFNA6
PIK-Akt signaling pathway
PTK2; MTCP1; FGF19; VTN; ANGPT4; LAMB1; PPP2R2A; GNG4; FOXO3; GNGT2
Toll-like receptor signaling pathway
MAPK11; RIPK1L; IFNA2; CCL3L1; CD40; IFNPHI3; IFNAR2; AKT3A; CCL3L3; TNF
RIG-I-like receptor signaling pathway
IFNB; RIPK1; IFNA7; MAPK10; MAPK11; IKBKE; ATG5; IL12BA; IFNA8; MAP3K1
Cytosolic DNA-sensing pathway
TREX1; IFNA16; POLR2F; POLR3A; POLR1D; CCL4L1; NFKBIAB; ZBP1; CCL4; IL33
Jak-STAT signaling pathway
CRFB4; EPO; Ifna15; PRL; IFNA8; IL2RGA; OSMR; GHR; SOS1; IFNAR1
Natural killer cell mediated cytotoxicity
SH3BP2; IFNGR1; MICA; CD244; TNFRSF10D; PPP3R1; MAP2K2; IFNA4; CD247; Ifna15
Tuberculosis
TLR4; IL23; FCGR3A; CLEC4E; NOS2; CORO1A; TRAF6; TLR9; AKT2; ATP6V0A2
Hepatitis C
IRF3; OAS1B; PIAS1; PIK3CB; HRAS; PPARA; IRF7; PPP2R1B; PIK3R2; BRAF
Hepatitis B
IL6; FASLG; IFNA2; ATP6AP1; NRAS; CCNA1; EP300; IKBKG; CREB3L2; IFNA8
Measles
IFNA1; MAP3K7; IL2RG; HSPA1A; TLR7; CCND1; IFNA12; IFIH1; TLR4; IFNGR1
Influenza A
NFKBIA; HSPA6; RELA; DDX58; HLA-DMB; PIK3CG; TNFRSF1A; PIK3CB; HLA-DMA; IKBKB
Herpes simplex infection
C3; MAP3K7; IFNA8; HLA-DRA; FASLG; IFNA3; IFNB; HLA-DQB1; HLA-E; TAB2
Autoi
IFNA7; IFNA2; HLA-DPB1; HLA-DRB1; Ifna11; Ifna15; CD40LG; CD80; H2-AB1; CD40
ne thyroid disease
TSHR; PRF1; HLA-DMB; CD86; IFNA21; HLA-DMA; CD40LG; H2-Q10; HLA-DOA; H2-AB1

Protein Function

IFNA16 has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA16 itself. We selected most functions IFNA16 had, and list some proteins which have the same functions with IFNA16. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein CMTM7; INHBA; CMTM1; FLT3LG; IFNA16; CSF3; HMGB1A; IFNG; IL7; NDR1
Function type I interferon receptor binding
Related Protein IFNK; OSTN; IFNA21; IFNW1; IFNPHI3; IFNA3; GM13285; IFNB; IFNPHI1; GM13279

Interacting Protein

IFNA16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA16 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA16.
PARP2

IFNA16 Related Articles

Miterski, B; Jaeckel, S; et al. The interferon gene cluster: a candidate region for MS predisposition?. GENES AND IMMUNITY 1:37-44(1999).