ifna16
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  • Official Full Name
  • interferon, alpha 16
  • Background
  • Interferon alpha-10 is a protein that in humans is encoded by the IFNA16 gene.
  • Synonyms
  • IFNA16; interferon, alpha 16; interferon alpha-16; IFN alphaO; IFN alpha N protein; Interferon alpha WA; IFN-alpha-16; IFN-alpha-N-protein; interferon alpha-WA; IFN-alphaO
Cat.#:IFNA16-46HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 16
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Cat.#:IFNA16-836HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFNA16 cell lysate
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Involved Pathway

IFNA16 involved in several pathways and played different roles in them. We selected most pathways IFNA16 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA16 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
GM2002; CXCL8; TNFRSF8; INHBA; CXCR6; PRLRA; IL4R; ACVR1; CCR1L1; Ccl21c
Regulation of autophagy
IFNA8; IFNA16; IFNA6; ULK1; IFNA4; ULK3; INS1; GABARAP; IFNG; IFNPHI1
PIK-Akt signaling pathway
VEGFC; GNB1; COL6A4; TEK; PIK3R1; PRKAA1; TRP53; PPP2R2A; SYK; FGF7
Toll-like receptor signaling pathway
RAC1A; TBK1; FADD; MAPK10; IFNA2; CD80; TRAF6; TOLLIP; CCL4L1; MAP2K4B
RIG-I-like receptor signaling pathway
IFNPHI1; IFNB1; RIPK1; IFNPHI3; SIKE1; ATG5; ATG12; IFNA4; NT5C3; NFKBIA
Cytosolic DNA-sensing pathway
LOC100033925; POLR3C; NFKBIAA; CCL4L2; IFNA10; IL6; IFNPHI3; MAVS; POLR1D; IFNA21
Jak-STAT signaling pathway
PIAS4; IL2RA; IL-15RA; PIK3CB; Ifnlr1; IFNAR2; M17; STAT4; CCND2A; PTPN11
Natural killer cell mediated cytotoxicity
SHC3; KIR2DS5; PIK3R3; KIR2DS2; Raet1a; FCGR3A; CD244; BRAF; ICAM1; ULBP1
Tuberculosis
NFYB; PIK3C3; Il23a; RHOA; FCER1G; CD209C; MAPK3; TNFRSF1A; CARD9; Pla2r1
Hepatitis C
IFNA1; IRF9; CLDN4; NFKBIA; OAS2; PPP2R2B; PPP2R2C; CLDN18; IFNA5; IFNA14
Hepatitis B
MAP2K2; PRKCB; CREB3L3; TNF; CXCL8; PCNA; AKT1; CASP9; PIK3R5; IFNA13
Measles
TBK1; EIF3H; IL1A; IFNA4; FAS; TNFRSF10C; TLR9; RCHY1; IFNA1; MAVS
Influenza A
IL-8; TBK1; IFIH1; HNRNPUL1; HLA-DPB1; BCL2L2-PABPN1; DDX39B; VDAC1; PIK3R1; RNASEL
Herpes simplex infection
PER2; PPP1CAB; SOCS3; TNFRSF1A; C3; HCFC1; MAPK8B; BF1; SFRS3B; CASP3B
Autoi
TPO; HLA-DPB1; IFNA10; HLA-DRB4; TG; HLA-DRA; H2-AB1; Fasl; Ifna15; IL5
ne thyroid disease
HLA-A; HLA-DOA; HLA-DRB4; IFNA14; CD80; HLA-F; H2-AB1; HLA-DRB5; TPO; IFNA10

Protein Function

IFNA16 has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA16 itself. We selected most functions IFNA16 had, and list some proteins which have the same functions with IFNA16. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein Ifna11; CMTM7; CMTM6; CER1; IL17A/F2; BMP3; BMP8A; BMP10; IL36B; IL26
Function type I interferon receptor binding
Related Protein IFNA2; IFNA16; IFNA3; IFNA21; IFNE; OSTN; IFNW1; IFNA8; IFNA6; IFNA1

Interacting Protein

IFNA16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA16 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA16.
PARP2

IFNA16 Related Articles

Miterski, B; Jaeckel, S; et al. The interferon gene cluster: a candidate region for MS predisposition?. GENES AND IMMUNITY 1:37-44(1999).