jund
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  • Official Full Name
  • jun D proto-oncogene
  • Background
  • The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]
  • Synonyms
  • JUND; jun D proto-oncogene; AP-1; transcription factor jun-D; JunD-FL isoform; activator protein 1;
Cat.#:JUND-785HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human JUND Protein, MYC/DDK-tagged
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Cat.#:JUND-312HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human JUND
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Cat.#:JUND-8440MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUND Protein
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Cat.#:JUND-3148RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUND Protein
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Cat.#:JUND-6855ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish JUND
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Involved Pathway

JUND involved in several pathways and played different roles in them. We selected most pathways JUND participated on our site, such as ATF-2 transcription factor network, AhR pathway, Corticotropin-releasing hormone, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUND were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ATF-2 transcription factor network
DUSP1; POU2F1; JDP2; KCNA3; JUN; DUSP10; HRK; DDIT3; MAPK14; CDK4
AhR pathway
JUND; AHR; CYP1A1; CDKN1B; AIP; CDC37; AHRR; JUN; CYP1A2; CDKN1A
Corticotropin-releasing hormone
ECE1; CRHR1; CRHR2; CYP21A2; ADRBK2; TCF4; PARP1; CRHBP; CASP12; TRIM28
EGFR1 Signaling Pathway
RBBP7; TNIP1; PTPN12; PITPNA; MAP3K2; GRB10; RGS5B; EPPK1; JUND; GRB14
Hypertrophy Model
IFRD1; HBEGFB; JUND; ADAM10A; DUSP14; MSTNB; WDR1; MSTN; MYOG; ANKRD1
Integrated Pancreatic Cancer Pathway
DAXX; TFF1; FKBP3; GPRC5A; BRF1; CD82; CST3; LEFTY1; CASP12; NOXA1
MAPK signaling pathway
NTF3; MINK1; MAPK3; MAPK8; NFATC3; FGF17; RRAS; MAP2K1; FLNA; RPS6KAL
Oncostatin M Signaling Pathway
JUND; CYR61

Protein Function

JUND has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUND itself. We selected most functions JUND had, and list some proteins which have the same functions with JUND. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein ZBTB7A; PPARA; MEIS1; RFX1; CRX; FEZF1; SMAD4; MEOX1; JDP2; POU1F1
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein RUNX3; SOX8; FLI1B; FOXP1; ETV5A; FOXA1; ETV6; SIM1; OVOL1; RUNX2B
Function enzyme binding
Related Protein PCBP2; VAPB; CBX3; Ar; HDAC1; HDAC10; UGT1A9; C2orf56; JUN; GSTM3
Function ligand-dependent nuclear receptor binding
Related Protein BAZ2A; ARID1A; MED1; SMARCE1; TRIP4; TRIM24; PPARGC1A; PROX1; SRA1; TADA3
Function protein binding
Related Protein CCDC109A; CHMP4A; PSMC2; TSPAN6; ARGLU1; SPANXD; AP5S1; C14orf169; TTPA; TEAD3
Function transcription coactivator activity
Related Protein PIAS1; TAF9; VGLL1; USP22; CITED2; MED21; RIPK3; TBPL1; SIX3; MCIN
Function transcription factor binding
Related Protein LEF1; TFDP1; MED25; MYOCD; MAPK9; MAPK1; DAXX; GTF2F1; DRAP1; HYAL1
Function transcription regulatory region DNA binding
Related Protein ZNF335; GABPB2; HIVEP2; SNCA; ATMIN; MESP1; TFE3; HIVEP3; NKX2-1; AIRE

Interacting Protein

JUND has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUND here. Most of them are supplied by our site. Hope this information will be useful for your research of JUND.
FOS; q7lyy4_9dela; FOSL2; ACTR3; MDM2; AR

JUND Related Articles

Matsumura, H; Ogata, Y; et al. Melatonin regulates human bone sialoprotein gene transcription. JOURNAL OF ORAL SCIENCE 56:67-76(2014).
Zhou, LM; Matsumura, H; et al. Protamine stimulates bone sialoprotein gene expression. GENE 516:228-237(2013).