This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 9 tandem leucine-rich repeats. Two transcript variants encoding the same protein have been found for this gene. Other variants may occur, but their full-length natures have not been characterized.
LRRC29; leucine rich repeat containing 29; F box and leucine rich repeat protein 9 , FBXL9; leucine-rich repeat-containing protein 29; FBL9; F box and leucine rich repeat protein 9; F box/LRR repeat protein 9; FBXL9; Leucine rich repeat containing protein 29; F-box protein FBL9; F-box/LRR-repeat protein 9; F-box and leucine-rich repeat protein 9
LRRC29 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRRC29 itself. We selected most functions LRRC29 had, and list some proteins which have the same functions with LRRC29. You can find most of the proteins on our site.
Function protein binding
Related Protein CRHBP; CDC20B; SLC25A18; IFT43; LSAMP; MIIP; SCO2; B9D2; ID4; DCP1A
LRRC29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRC29 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRC29.
LRRC29 Related Articles
Vaccari, JPD; Lotocki, G; et al. Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 29:1251-1261(2009).