• Official Full Name
  • microtubule-associated protein 4
  • Background
  • The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Synonyms
  • MAP4; microtubule-associated protein 4; MAP-4; Mtap-4; AA407148
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MAP4
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAP4 protein, His & GST-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Map4 protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MTAP4 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MAP4 Protein
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Map4 protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MAP4 Protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human MAP4 293 Cell Lysate
Source (Host):Species:Human
Product nameRecombinant Human MAP4 293 Cell Lysate

Protein Function

MAP4 has several biochemical functions, for example, microtubule binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP4 itself. We selected most functions MAP4 had, and list some proteins which have the same functions with MAP4. You can find most of the proteins on our site.
Related Protein
Function microtubule binding
Related Protein KATNA1; EML2; NPSNL; VPS41; DYNC1I1; KIF17; KIF4A; ZNF207; HDAC6; KIF16B
Function poly(A) RNA binding
Related Protein PDAP1; UBAP2L; EIF2S2; FUBP1; PARN; FXR1; PNO1; SUPT5H; RBM39; MAP4
Function protein binding
Related Protein DCDC2B; LOC149950; EPS8L1; POC5; AKR1B10; PMM2; ZBP1; FRS2; THRA; DYNLT1
Function structural molecule activity
Related Protein CLDN15A; PSMD13; KRT13; KRT86; MPZ; CLTB; CLDN15; KRT95; KRT40; CLDNH

Interacting Protein

MAP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP4.
Csnk1d; NCK1; PLCG1; PIK3R1; FYCO1; LDLR; ENO2; GSK3B; TERF1; tktA; q7ard3_yerpe; pepP; hisD; POT1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; ssrna_ug

MAP4 Related Articles

Zhang, LS; Miao, L; et al. Multiple antigen peptide mimetics containing gp41 membrane-proximal external region elicit broad neutralizing antibodies against human immunodeficiency virus type 1 in guinea pigs. JOURNAL OF PEPTIDE SCIENCE 19:491-498(2013).
Du, T; La Fontaine, SL; et al. Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays. PROTEOMICS 8:1819-1831(2008).