• Official Full Name
  • mitochondrial ribosomal protein S11
  • Background
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.
  • Synonyms
  • MRPS11; mitochondrial ribosomal protein S11; 28S ribosomal protein S11, mitochondrial; cervical cancer proto oncogene 2; FLJ22512; FLJ23406; HCC 2; mitochondrial; 28S ribosomal protein S11; 28S ribosomal protein S11, mitochondrial precursor; Cervical cancer proto oncogene 2 protein; Cervical cancer proto-oncogene 2 protein; HCC-2; MRP S11; MRP-S11; RPMS11; RT11_HUMAN; S11mt
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRPS11 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRPS11, His-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MRPS11 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MRPS11
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MRPS11
Source (Host):Species:Human
Product nameRecombinant Human MRPS11 293 Cell Lysate

Involved Pathway

MRPS11 involved in several pathways and played different roles in them. We selected most pathways MRPS11 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RPL23A; RPS3; RPL10L; RPSA; RPL21; MRPL10; RPL14; RPS12; RPS10; RPL8

Protein Function

MRPS11 has several biochemical functions, for example, mRNA 5-UTR binding, poly(A) RNA binding, small ribosomal subunit rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS11 itself. We selected most functions MRPS11 had, and list some proteins which have the same functions with MRPS11. You can find most of the proteins on our site.
Related Protein
Function mRNA 5-UTR binding
Related Protein LARP1; RPS14; IGF2BP3; DDX3X; MRPS11; IGF2BP1; IGF2BP2
Function poly(A) RNA binding
Related Protein KTN1; RBM10; NUDT21; RBMS2; HRSP12; STXBP1; FAM98B; POP7; EPPK1; ANP32A
Function small ribosomal subunit rRNA binding
Related Protein UTP23; CIRBP; MRPS11; NSUN4; MRPS6; RPS13; RPS14; RPS3
Function structural constituent of ribosome
Related Protein MRPL10; MRPS14; MRPL52; MRPL2; RPS4X; RPL19; MRPL47; RPS26L; MRPL51; RPS8

Interacting Protein

MRPS11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS11.
SRPK2; SRPK1; ssdna_dtdc; ICT1; SLX4; MAP1LC3A

MRPS11 Related Articles

Choi, SJ; Park, EJ; et al. Inheritance pattern of chloroplast and mitochondrial genomes in artificial hybrids of Porphyra yezoensis (Rhodophyta). FISHERIES SCIENCE 74:822-829(2008).
Zikova, A; Panigrahi, AK; et al. Trypanosoma brucei mitochondrial ribosomes. MOLECULAR & CELLULAR PROTEOMICS 7:1286-1296(2008).