pim3
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  • Official Full Name
  • pim-3 oncogene
  • Background
  • The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is;overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the;regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a;selective advantage in tumorigenesis.
  • Synonyms
  • PIM3; pim-3 oncogene; serine/threonine-protein kinase pim-3; serine/threonine kinase Pim-3; pim-3
Cat.#:Pim3-116HTag:His
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human Pim-3, His-tagged
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Cat.#:PIM3-1461HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PIM3 protein, His & T7-tagged
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Cat.#:Pim3-1081HTag:GST
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Pim3 protein, GST-tagged
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Cat.#:Pim3-1081MTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Pim3, GST-tagged
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Cat.#:PIM3-4466RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PIM3 Protein
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Cat.#:PIM3-3453ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PIM3
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Cat.#:PIM3-1457MTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Mouse
Product nameRecombinant Mouse PIM3 (Active), GST-tagged
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Protein Function

PIM3 has several biochemical functions, for example, ATP binding, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIM3 itself. We selected most functions PIM3 had, and list some proteins which have the same functions with PIM3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ATP1A1A.3; ATP1A3B; HELZ; KIAA1804; PRKACA; CFTR; RARS; NEK10; SLKA; VCP
Function protein binding
Related Protein C1QA; MAP3K2; VEGFAA; CAMK2B; CPT1C; FANCB; PTPRS; FBXO9; DDX18; GNL3
Function protein serine/threonine kinase activity
Related Protein CDK15; CSNK1A1; BMPR1BA; MARK1; NEK12; ADCK2; MAP3K10; VPRBP; TSSK4; GRK7A

Interacting Protein

PIM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIM3.
MDM2; HSP90AB1

PIM3 Related Articles

Lopane, C; Goffredo, V; et al. LPA6 promotes growth and tumorigenicity of hepatocellular carcinoma via activation of PIM-3 proto-oncogene kinase. EUROPEAN JOURNAL OF CANCER 50:161-161(2014).
Guo, Q; Lan, PX; et al. Immunotherapy for Hepatoma Using a Dual-Function Vector with Both Immunostimulatory and Pim-3-Silencing Effects. MOLECULAR CANCER THERAPEUTICS 13:1503-1513(2014).