Recombinant Human PIM3 protein, His & T7-tagged

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Recombinant Human PIM3 protein, His & T7-tagged

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Cat.No. : PIM3-1461H
Product Overview : Recombinant Human PIM3 aa. (Met1~Leu326 (Accession # Q86V86)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 39.6kDa
Protein length : Met1~Leu326 (Accession # Q86V86)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 5.8
SDS-PAGE :

Gene Name : PIM3 Pim-3 proto-oncogene, serine/threonine kinase [ Homo sapiens (human) ]
Official Symbol : PIM3
Synonyms : PIM3; Pim-3 proto-oncogene, serine/threonine kinase; pim-3; serine/threonine-protein kinase pim-3; pim-3 oncogene; serine/threonine kinase Pim-3
Gene ID : 415116
mRNA Refseq : NM_001001852.3
Protein Refseq : NP_001001852.2
UniProt ID : Q86V86

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