Recombinant Human PIM3 protein, His & T7-tagged

• Cat.No.: PIM3-1461H
• Product Overview: Recombinant Human PIM3 aa. (Met1~Leu326 (Accession # Q86V86)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Met1~Leu326
• Description: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39.6kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5.8

Gene Information

• Gene Name: PIM3 Pim-3 proto-oncogene, serine/threonine kinase [ Homo sapiens (human) ]
• Official Symbol: PIM3
• Synonyms: PIM3; Pim-3 proto-oncogene, serine/threonine kinase; pim-3; serine/threonine-protein kinase pim-3; pim-3 oncogene; serine/threonine kinase Pim-3
• Gene ID: 415116
• mRNA Refseq: NM_001001852.3
• Protein Refseq: NP_001001852.2
• UniProt ID: Q86V86