PPP3CA Protein, protein phosphatase 3, catalytic subunit, alpha isozyme


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Official Full Name protein phosphatase 3, catalytic subunit, alpha isozyme
Background Calcineurin (CN) is a protein phosphatase also known as protein phosphatase 3, PPP3CA, and calcium-dependent serine-threonine phosphatase, and formerly known as protein phosphatase 2B (PP2B).It activates the T cells of the immune system and can be blo
Synonyms PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; CALN, CALNA, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); serine/thr
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP3CA-001H Recombinant Human PPP3CA & PPP3R1 Protein E.coli
    Human PPP3CA&PPP3R1-626H Recombinant Human PPP3CA&PPP3R1 Sf21 Insect Cell N/A
    Human PPP3CA-001HCL Recombinant Human PPP3CA cell lysate Insect Cell N/A
    Human PPP3CA-158H Recombinant Human PPP3CA Mammalian Cell His
    Human PPP3CA-1922H Recombinant Human PPP3CA, GST-tagged E.coli GST
    Human PPP3CA-26743TH Recombinant Human PPP3CA, His-tagged E.coli His
    Human PPP3CA-5255H Recombinant Human PPP3CA/PPP3R1 Protein E.coli N/A
    Human PPP3CA-7365H Recombinant Human PPP3CA, His tagged Insect Cell His
    Human PPP3CA-951H Recombinant Human PPP3CA, His-tagged E.coli His
    Rat PPP3CA-4639R Recombinant Rat PPP3CA Protein Mammalian Cell His
    Rhesus Macaque PPP3CA-3576R Recombinant Rhesus monkey PPP3CA Protein, His-tagged Mammalian Cell His
    Zebrafish PPP3CA-7831Z Recombinant Zebrafish PPP3CA Mammalian Cell His

    PPP3CA involved in several pathways and played different roles in them. We selected most pathways PPP3CA participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3CA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway PDGFAA; RASGRF2; MAP3K1; PRKACBA; TP53; TRAF6; GADD45BB; HSP70L; SRF; MAP2K4A
    Calcium signaling pathway ADORA2AB; PLCG1; TACR1; ATP2A3; DRD1A; EDNRB2; PRKACBA; LTB4R2; MYLK3; CALM2
    cGMP-PKG signaling pathway ATP1B3; LOC100328615; AGTR1A; CALM3; NFATC3; AKT2; PPP1R12A; PDE5A; BNP; FXYD2
    Wnt signaling pathway BAMBI; PPP3CC; VANGL1; FZD7A; WNT2B; LRP5; FZD9B; NLK; NFATC4; PRKACAB
    Axon guidance UNC5D; SPRED3; NETO2; FRS2A; SCN4A; PHB; NTN1B; ARPC1A; NFATC3; PPP3R1
    VEGF signaling pathway MAPK3; PPP3CB; PPP3R1B; RAC3A; PIK3R2; MAPK1; PIK3CG; MAP2K2A; PTGS2B; VEGFAA
    Osteoclast differentiation LILRA1; SYK; MAP2K6; STAT1; TGFB2; CAMK4; CYLD; FYN; FCGR2B; FCGR4
    Natural killer cell mediated cytotoxicity FCGR3B; NFATC1; Casp3; PIK3CA; HLA-G; IFNA7; KLRC2; Ifna15; MAP2K2; LCK
    T cell receptor signaling pathway VAV2; PDCD1; DEF6A; NFKBIB; VAV3; RELA; IKBKB; MAP2K1; NFATC1; GRAP2
    B cell receptor signaling pathway INPPL1; RAC2; RASGRP3; SOS1; CDK4; PTPN18; LILRB3; CARD11; CMTM3; LAT2
    Long-term potentiation GRIN2A; ATF4; CALM3; PLCB2; PLCB1; KRAS; PRKCA; PPP3CA; RAP1A; EP300
    Glutamatergic synapse GNAQ; GNG11; GRM8; GRIA3; GLUL; GNGT1; SLC38A2; PRKCA; SHANK1; PRKACB
    Dopaminergic synapse ARNTL; DRD4; PPP3CB; GNAO1; GNB4; CALML3; GNAQ; SLC18A1; DDC; GNG11
    Oxytocin signaling pathway PRKACG; GUCY1A3; ACTB; RCAN1; PIK3CG; PRKAB2; CD38; PRKAA2; PLA2G4C; CAMK1
    Glucagon signaling pathway CALM2; CRTC2; GYS2; PRKAA1; PPP3CA; PDHB; SLC2A1; PHKB; PYGB; PFKFB1
    Renin secretion CLCA1; ITPR3; PDE3B; GUCY1B3; ACE; AQP1; PLCB3; REN; PPP3R2; PDE1B
    Alzheimers disease COX6C; NDUFB7; APP; SDHC; BID; COX8C; BACE1; MAPK1; ITPR1; ATP5O
    Amyotrophic lateral sclerosis (ALS) SOD1; GRIA2; PPP3R1; TRP53; NOS1; TNF; DERL1; MAP3K5; DAXX; TOMM40
    Amphetamine addiction DDC; CAMK2D; MAOA; PRKCB; GNAS; CREB3L1; CALML5; CALML3; GRIN2B; CALM1
    Tuberculosis Ifna15; MAPK3; Ifna11; PPP3CC; ITGB2L; FCGR2B; CD209A; CD74; RFXANK; RAF1

    PPP3CA has several biochemical functions, for example, calcium ion binding, calmodulin binding, calmodulin-dependent protein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3CA itself. We selected most functions PPP3CA had, and list some proteins which have the same functions with PPP3CA. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding MATN3A; PCDHB12; RPH3AL; STIM2; PLCZ1; CASQ1A; DGKG; SLC24A1; MAN1C1; CDH19
    calmodulin binding CAMSAP1L1; TRPM4; MYO1F; SNTB1; C2orf62; ITPKB; CAMK2D; STRN; CNN3A; ATP2B1
    calmodulin-dependent protein phosphatase activity PPP3CB; PPP3CA; PPM1F; PPM1A
    drug binding SRP54; PPP3CA; PDE4C; UGT1A7; MT3; CHRNB4; GSTP2; DAAM2; HMGCS1; PDE4D
    enzyme binding TUT1; UGT1A2; RCOR3; CCDC99; GOT2; CYP2A6; HIF1A; Il6ra; TP53; APOA5
    protein binding KRTAP4-12; UBE2M; UBE2IB; APLF; FAM134C; PDCD6IP; PRKAG1; RBFOX1; MYO18A; NTF4
    protein dimerization activity HER2; NPAS4; AHRRA; EBF4; POU2F3; TCF3A; SREBF1; ID4; HER3; HER4.2
    protein heterodimerization activity HIST2H2AA4; ITGB1B; TGFB2; NPAS4; TYRP1; UGT1A6B; LIFR; HNF1A; UGT1A6; NEUROD2
    protein serine/threonine phosphatase activity PPM1J; PPM1DB; PPP5C; PPP4C; CDC14AB; CTDNEP1B; CDC14AA; PPP2R2A; MTMR3; ILKAP

    PPP3CA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3CA here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3CA.

    PPP3R1; GRB2; C16orf74; Cacng8; USP14; LASP1; Kcnj8; Nfatc1; ABL1

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